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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS2
All Species:
8.48
Human Site:
S95
Identified Species:
15.56
UniProt:
Q9NP85
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP85
NP_055440.1
383
42201
S95
R
P
E
E
G
T
K
S
S
G
L
G
A
C
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090776
288
31597
V35
G
P
C
G
W
I
L
V
A
F
S
F
L
F
T
Dog
Lupus familis
XP_547443
542
59797
S254
W
P
R
K
S
T
K
S
S
G
L
G
A
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91X05
385
42318
P97
R
P
E
E
G
I
K
P
S
G
L
G
A
C
E
Rat
Rattus norvegicus
Q8K4G9
383
42368
P95
R
P
E
E
G
I
K
P
S
G
L
G
A
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515734
392
44086
S104
R
Q
E
E
G
I
K
S
S
S
L
G
A
C
E
Chicken
Gallus gallus
XP_422265
382
42762
P95
Q
E
E
G
M
K
S
P
G
L
N
I
C
E
W
Frog
Xenopus laevis
NP_001080862
281
30963
C28
V
S
E
G
G
L
G
C
C
G
W
F
L
V
I
Zebra Danio
Brachydanio rerio
NP_001018155
390
43665
K106
G
P
G
E
G
L
K
K
K
Y
L
G
V
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZA4
505
57508
S168
R
R
A
D
E
E
I
S
D
K
A
S
T
C
G
Honey Bee
Apis mellifera
XP_001123020
273
30388
V20
D
T
C
K
N
I
L
V
I
L
S
W
I
I
V
Nematode Worm
Caenorhab. elegans
Q27433
481
51881
Q111
K
E
E
K
A
N
I
Q
N
E
F
G
V
C
G
Sea Urchin
Strong. purpuratus
XP_783694
283
31056
G30
N
A
S
E
G
G
M
G
C
C
G
F
L
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
38.1
58.4
N.A.
85.9
85.1
N.A.
74.7
61.8
39.1
44.8
N.A.
32
35.7
32.2
38.3
Protein Similarity:
100
N.A.
55
63.4
N.A.
91.4
91.6
N.A.
83.4
75.1
55.3
62.5
N.A.
49.1
53
50.3
55
P-Site Identity:
100
N.A.
6.6
73.3
N.A.
86.6
86.6
N.A.
80
6.6
20
53.3
N.A.
20
0
20
13.3
P-Site Similarity:
100
N.A.
13.3
80
N.A.
86.6
86.6
N.A.
80
13.3
20
53.3
N.A.
26.6
6.6
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
0
0
8
0
8
0
39
0
0
% A
% Cys:
0
0
16
0
0
0
0
8
16
8
0
0
8
62
0
% C
% Asp:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
16
54
47
8
8
0
0
0
8
0
0
0
8
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
24
0
8
0
% F
% Gly:
16
0
8
24
54
8
8
8
8
39
8
54
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
39
16
0
8
0
0
8
8
8
8
% I
% Lys:
8
0
0
24
0
8
47
8
8
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
16
16
0
0
16
47
0
24
8
0
% L
% Met:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
8
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
47
0
0
0
0
0
24
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
39
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
8
0
8
31
39
8
16
8
0
0
0
% S
% Thr:
0
8
0
0
0
16
0
0
0
0
0
0
8
0
16
% T
% Val:
8
0
0
0
0
0
0
16
0
0
0
0
16
8
8
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
8
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _