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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A2
All Species:
12.12
Human Site:
S159
Identified Species:
22.22
UniProt:
Q9NP94
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP94
NP_055394.2
309
32742
S159
H
G
H
L
P
S
P
S
K
G
P
L
R
A
L
Chimpanzee
Pan troglodytes
XP_520676
309
32797
S159
H
G
H
L
P
S
P
S
K
S
P
L
R
A
L
Rhesus Macaque
Macaca mulatta
XP_001093382
309
33153
S159
H
G
H
L
P
S
P
S
K
S
P
L
R
A
L
Dog
Lupus familis
XP_539681
425
44340
S275
H
G
P
P
P
S
P
S
K
G
P
L
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ03
324
34260
A174
Q
A
G
G
T
P
A
A
P
S
A
L
R
A
C
Rat
Rattus norvegicus
Q5U1X7
317
33945
R167
L
R
L
R
E
L
G
R
P
G
P
L
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521563
301
31113
G153
P
L
P
A
P
A
R
G
S
L
R
A
L
V
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P59889
302
32803
A153
H
V
H
V
D
F
H
A
H
S
S
F
R
S
F
Tiger Blowfish
Takifugu rubipres
Q6QQT1
302
33019
A153
H
V
H
V
D
F
Q
A
H
S
P
F
R
S
F
Fruit Fly
Dros. melanogaster
NP_525107
352
37880
D194
H
M
P
V
P
A
D
D
G
S
S
A
R
G
L
Honey Bee
Apis mellifera
XP_395274
519
56696
K274
S
H
V
T
I
T
K
K
K
A
S
I
Q
G
L
Nematode Worm
Caenorhab. elegans
NP_001122755
337
36573
K154
P
W
V
V
S
D
E
K
R
N
L
L
K
S
L
Sea Urchin
Strong. purpuratus
XP_794867
287
30706
P138
A
S
I
T
V
L
Q
P
L
T
S
F
R
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.4
58.3
N.A.
29
29.6
N.A.
60.8
N.A.
N.A.
34.9
35.2
26.1
21
26.4
25.8
Protein Similarity:
100
99.3
97.4
62.5
N.A.
46.9
45.7
N.A.
70.5
N.A.
N.A.
51.4
50.8
43.4
36.2
42.4
42.7
P-Site Identity:
100
93.3
93.3
73.3
N.A.
20
33.3
N.A.
13.3
N.A.
N.A.
20
26.6
26.6
13.3
13.3
13.3
P-Site Similarity:
100
93.3
93.3
80
N.A.
26.6
33.3
N.A.
20
N.A.
N.A.
40
46.6
40
33.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
16
8
24
0
8
8
16
0
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
16
8
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
16
0
0
0
0
0
24
0
0
16
% F
% Gly:
0
31
8
8
0
0
8
8
8
24
0
0
8
16
0
% G
% His:
54
8
39
0
0
0
8
0
16
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
16
39
0
0
0
8
0
0
% K
% Leu:
8
8
8
24
0
16
0
0
8
8
8
54
8
8
70
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
16
0
24
8
47
8
31
8
16
0
47
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
16
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
8
0
0
8
8
8
0
8
0
70
0
0
% R
% Ser:
8
8
0
0
8
31
0
31
8
47
31
0
0
31
0
% S
% Thr:
0
0
0
16
8
8
0
0
0
8
0
0
0
0
0
% T
% Val:
0
16
16
31
8
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _