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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP25
All Species:
15.45
Human Site:
S126
Identified Species:
37.78
UniProt:
Q9NPA2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPA2
NP_071913.1
562
62554
S126
T
L
T
W
R
V
R
S
F
P
Q
S
S
Q
L
Chimpanzee
Pan troglodytes
XP_509485
604
66817
T144
N
L
S
W
R
V
R
T
F
P
R
D
S
P
L
Rhesus Macaque
Macaca mulatta
XP_001091146
562
62740
S126
T
L
T
W
R
V
R
S
F
P
Q
S
S
Q
L
Dog
Lupus familis
XP_547166
761
84740
K116
L
S
G
S
M
W
R
K
R
T
L
T
W
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U435
615
68477
S181
T
L
T
W
S
I
R
S
F
S
Q
K
S
Q
L
Rat
Rattus norvegicus
Q10739
582
66062
N130
E
I
T
F
C
I
Q
N
Y
T
P
K
V
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515193
574
63134
L103
S
F
P
R
A
S
A
L
S
M
D
T
I
R
T
Chicken
Gallus gallus
XP_415092
592
66478
T137
N
L
S
W
R
V
R
T
F
P
K
E
S
H
L
Frog
Xenopus laevis
Q11005
477
54423
R92
R
F
V
L
S
G
G
R
W
D
K
T
N
L
T
Zebra Danio
Brachydanio rerio
XP_002663942
573
64445
N131
D
I
T
W
S
V
Q
N
Y
P
S
V
H
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.3
94.8
60.4
N.A.
70.5
38.1
N.A.
64.9
44.5
34.7
46.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.7
95.9
64.3
N.A.
77.5
53.4
N.A.
73.3
57.9
47.1
59.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
6.6
N.A.
73.3
6.6
N.A.
0
60
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
26.6
N.A.
80
46.6
N.A.
20
80
26.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
20
0
10
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
10
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
0
20
0
0
0
20
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
20
20
0
10
0
% K
% Leu:
10
50
0
10
0
0
0
10
0
0
10
0
0
10
50
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
20
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
50
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
20
0
0
0
30
0
0
30
0
% Q
% Arg:
10
0
0
10
40
0
60
10
10
0
10
0
0
20
10
% R
% Ser:
10
10
20
10
30
10
0
30
10
10
10
20
50
0
0
% S
% Thr:
30
0
50
0
0
0
0
20
0
20
0
30
0
0
20
% T
% Val:
0
0
10
0
0
50
0
0
0
0
0
10
10
0
10
% V
% Trp:
0
0
0
60
0
10
0
0
10
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _