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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARD6A All Species: 24.85
Human Site: S268 Identified Species: 49.7
UniProt: Q9NPB6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPB6 NP_001032358.1 346 37388 S268 G R L T G P P S A G P G P A E
Chimpanzee Pan troglodytes XP_511037 346 37345 S268 G R L T G P P S A G P G P A E
Rhesus Macaque Macaca mulatta XP_001092684 345 37352 S268 G R L T G P P S A G P G P A E
Dog Lupus familis XP_546876 347 37080 S269 G R L T G P S S A G P G P T E
Cat Felis silvestris
Mouse Mus musculus Q9Z101 346 37315 S268 G R L T G P S S V G P G P T D
Rat Rattus norvegicus Q6B4M5 346 37380 S268 G R L T G P S S V G P G P T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516968 349 37646 L267 R P S T S A A L P A P P A P E
Chicken Gallus gallus XP_425103 358 38540 S265 A S G S S G V S T D S T P S Q
Frog Xenopus laevis NP_001081992 377 41958 S269 N S G S S G Q S T D S S T S V
Zebra Danio Brachydanio rerio NP_001093521 385 41919 S264 F K T S A G N S S A G S R G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAN2 309 34201 M234 L D Q V T D M M V A N A H N L
Sea Urchin Strong. purpuratus XP_792763 376 41713 S275 Q H L G V S S S L S Q S M A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 78.9 N.A. 93 92.4 N.A. 77.3 63.4 49.3 51.4 N.A. N.A. N.A. 45.6 44.6
Protein Similarity: 100 99.7 99.1 80.9 N.A. 94.5 94.2 N.A. 83.6 77 66 65.7 N.A. N.A. N.A. 60.6 58.7
P-Site Identity: 100 100 100 86.6 N.A. 73.3 73.3 N.A. 20 13.3 6.6 6.6 N.A. N.A. N.A. 0 20
P-Site Similarity: 100 100 100 86.6 N.A. 80 80 N.A. 20 33.3 20 26.6 N.A. N.A. N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 9 9 0 34 25 0 9 9 34 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 9 0 0 0 17 0 0 0 0 17 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 17 9 50 25 0 0 0 50 9 50 0 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 59 0 0 0 0 9 9 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 9 9 0 0 0 0 9 0 0 % M
% Asn: 9 0 0 0 0 0 9 0 0 0 9 0 0 9 0 % N
% Pro: 0 9 0 0 0 50 25 0 9 0 59 9 59 9 0 % P
% Gln: 9 0 9 0 0 0 9 0 0 0 9 0 0 0 9 % Q
% Arg: 9 50 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 17 9 25 25 9 34 84 9 9 17 25 0 17 17 % S
% Thr: 0 0 9 59 9 0 0 0 17 0 0 9 9 25 0 % T
% Val: 0 0 0 9 9 0 9 0 25 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _