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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDE5
All Species:
23.03
Human Site:
S639
Identified Species:
46.06
UniProt:
Q9NPB8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPB8
NP_062539.1
672
76035
S639
Q
E
L
P
E
L
K
S
C
L
C
P
T
V
S
Chimpanzee
Pan troglodytes
XP_514503
672
75988
S639
Q
E
L
P
E
L
K
S
C
L
C
P
T
V
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542901
672
75839
S639
Q
E
L
P
E
L
K
S
C
L
C
P
T
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0L9
675
76561
N642
Q
E
L
P
E
L
K
N
C
L
C
P
T
V
S
Rat
Rattus norvegicus
Q80VJ4
672
76251
N639
R
E
L
P
E
L
K
N
C
L
C
P
T
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512882
675
76401
S641
K
E
L
P
E
L
K
S
C
L
C
P
T
V
S
Chicken
Gallus gallus
XP_419376
678
77021
S640
K
E
L
P
E
L
K
S
C
V
C
P
T
V
S
Frog
Xenopus laevis
NP_001090135
678
77016
S645
L
P
A
E
M
L
K
S
C
A
C
P
V
F
N
Zebra Danio
Brachydanio rerio
NP_001103993
666
75129
A635
K
E
V
I
Q
T
C
A
C
S
T
Y
S
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608804
707
80440
K681
L
Q
A
K
D
S
Q
K
E
L
L
K
L
Q
A
Honey Bee
Apis mellifera
XP_393601
758
85849
T670
S
R
N
M
I
T
T
T
S
T
T
T
S
F
A
Nematode Worm
Caenorhab. elegans
Q10003
796
90813
S726
E
Q
K
R
A
L
L
S
C
S
G
A
S
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97.4
N.A.
92.4
91.2
N.A.
88.4
77.2
72.1
61.1
N.A.
31.6
23.7
28.3
N.A.
Protein Similarity:
100
99.8
N.A.
98.9
N.A.
97
96.2
N.A.
93.6
86.8
84.9
76.9
N.A.
50.6
43.1
46.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
93.3
86.6
40
13.3
N.A.
6.6
0
20
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
46.6
53.3
N.A.
33.3
20
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
0
0
9
0
9
0
9
0
0
17
% A
% Cys:
0
0
0
0
0
0
9
0
84
0
67
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
67
0
9
59
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
25
0
9
9
0
0
67
9
0
0
0
9
0
0
0
% K
% Leu:
17
0
59
0
0
75
9
0
0
59
9
0
9
0
0
% L
% Met:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
17
0
0
0
0
0
0
9
% N
% Pro:
0
9
0
59
0
0
0
0
0
0
0
67
0
0
17
% P
% Gln:
34
17
0
0
9
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
9
0
59
9
17
0
0
25
0
59
% S
% Thr:
0
0
0
0
0
17
9
9
0
9
17
9
59
9
0
% T
% Val:
0
0
9
0
0
0
0
0
0
9
0
0
9
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _