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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK9
All Species:
15.15
Human Site:
Y286
Identified Species:
33.33
UniProt:
Q9NPC2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPC2
NP_057685.1
374
42264
Y286
P
R
P
S
R
P
R
Y
K
A
D
V
P
D
L
Chimpanzee
Pan troglodytes
XP_001152552
330
36183
V243
G
A
F
L
N
L
V
V
L
R
F
L
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001099894
470
51850
Y382
P
R
P
S
R
P
R
Y
K
A
D
V
A
D
L
Dog
Lupus familis
XP_539178
497
53420
Y409
A
R
Q
G
R
P
R
Y
K
A
D
A
P
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3LS21
402
44892
Y286
R
K
R
H
H
A
M
Y
F
L
R
K
Y
G
R
Rat
Rattus norvegicus
Q9ES08
396
44339
Y286
R
K
R
H
H
P
M
Y
F
L
R
K
Y
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513444
490
53222
P390
V
A
G
V
G
R
D
P
R
R
G
R
P
P
R
Chicken
Gallus gallus
XP_425942
374
42568
Y286
S
Q
H
G
R
P
R
Y
K
A
E
V
T
D
L
Frog
Xenopus laevis
Q63ZI0
374
42700
Y286
T
P
H
G
R
Q
R
Y
K
A
E
V
T
D
L
Zebra Danio
Brachydanio rerio
NP_001122021
399
45150
R286
T
L
Q
R
S
R
R
R
R
E
Q
Q
Q
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
V242
S
A
A
M
N
L
L
V
L
R
F
L
T
M
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
78.9
60.5
N.A.
68.9
69.6
N.A.
63.8
90.9
89.5
77.6
N.A.
N.A.
N.A.
48.4
N.A.
Protein Similarity:
100
64.1
79.1
66.1
N.A.
77.6
79.5
N.A.
70
95.9
93.5
86.7
N.A.
N.A.
N.A.
63.6
N.A.
P-Site Identity:
100
0
93.3
73.3
N.A.
6.6
13.3
N.A.
6.6
60
53.3
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
6.6
93.3
73.3
N.A.
13.3
20
N.A.
13.3
73.3
60
20
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
10
0
0
10
0
0
0
46
0
10
19
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
28
0
0
46
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
19
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
19
0
19
0
0
0
0
% F
% Gly:
10
0
10
28
10
0
0
0
0
0
10
0
0
19
0
% G
% His:
0
0
19
19
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
0
0
0
0
46
0
0
19
0
0
0
% K
% Leu:
0
10
0
10
0
19
10
0
19
19
0
19
0
0
46
% L
% Met:
0
0
0
10
0
0
19
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
19
10
19
0
0
46
0
10
0
0
0
0
28
10
0
% P
% Gln:
0
10
19
0
0
10
0
0
0
0
10
10
10
0
0
% Q
% Arg:
19
28
19
10
46
19
55
10
19
28
19
10
0
0
37
% R
% Ser:
19
0
0
19
10
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
19
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% T
% Val:
10
0
0
10
0
0
10
19
0
0
0
37
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _