KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC4
All Species:
18.79
Human Site:
S61
Identified Species:
31.79
UniProt:
Q9NPD3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPD3
NP_061910.1
245
26383
S61
G
P
H
E
I
R
G
S
R
A
R
A
L
P
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539207
245
26416
S61
G
P
H
E
I
R
G
S
R
A
R
A
L
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q921I9
245
26231
S61
G
P
H
E
I
R
G
S
R
S
R
A
L
P
D
Rat
Rattus norvegicus
NP_001128332
245
26372
S61
G
P
H
E
I
R
G
S
R
S
R
A
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515504
245
26566
L61
G
P
H
E
M
R
G
L
R
S
R
A
L
P
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088679
249
27385
S61
G
P
H
E
I
R
G
S
R
S
K
M
L
H
D
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
R81
G
P
K
E
T
E
R
R
D
E
T
D
M
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609618
246
27003
H57
L
A
A
V
Y
G
P
H
Q
A
K
G
N
Q
T
Honey Bee
Apis mellifera
XP_395806
268
29368
S66
P
R
N
S
T
G
R
S
T
S
K
I
T
K
G
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
K56
V
Y
G
P
Y
E
G
K
S
S
K
R
I
E
D
Sea Urchin
Strong. purpuratus
XP_785829
192
21229
N34
F
S
T
N
E
R
K
N
R
P
Q
G
D
R
K
Poplar Tree
Populus trichocarpa
XP_002320845
241
26549
N57
Y
G
P
R
E
V
Q
N
R
S
Q
Q
I
N
D
Maize
Zea mays
NP_001131612
242
26471
K59
G
P
R
E
V
Q
N
K
G
Q
Q
V
N
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46948
246
27542
K62
G
P
K
E
P
R
L
K
S
Q
M
D
T
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.9
N.A.
95.9
97.5
N.A.
84.9
N.A.
79.5
30.2
N.A.
52.4
46.6
43.6
46.1
Protein Similarity:
100
N.A.
N.A.
99.1
N.A.
98.7
100
N.A.
92.6
N.A.
90.3
45.7
N.A.
69.9
60.8
63.2
63.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
80
N.A.
73.3
20
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
26.6
N.A.
20
26.6
33.3
26.6
Percent
Protein Identity:
49.8
47.3
N.A.
N.A.
34.9
N.A.
Protein Similarity:
71.8
67.7
N.A.
N.A.
56.1
N.A.
P-Site Identity:
13.3
20
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
40
40
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
22
0
36
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
15
8
0
58
% D
% Glu:
0
0
0
65
15
15
0
0
0
8
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
65
8
8
0
0
15
50
0
8
0
0
15
0
0
8
% G
% His:
0
0
43
0
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
36
0
0
0
0
0
0
8
15
0
0
% I
% Lys:
0
0
15
0
0
0
8
22
0
0
29
0
0
15
22
% K
% Leu:
8
0
0
0
0
0
8
8
0
0
0
0
43
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
8
8
0
0
% M
% Asn:
0
0
8
8
0
0
8
15
0
0
0
0
15
8
0
% N
% Pro:
8
65
8
8
8
0
8
0
0
8
0
0
0
36
0
% P
% Gln:
0
0
0
0
0
8
8
0
8
15
22
8
0
8
0
% Q
% Arg:
0
8
8
8
0
58
15
8
58
0
36
8
0
8
0
% R
% Ser:
0
8
0
8
0
0
0
43
15
50
0
0
0
15
0
% S
% Thr:
0
0
8
0
15
0
0
0
8
0
8
0
15
0
15
% T
% Val:
8
0
0
8
8
8
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _