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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC4
All Species:
32.73
Human Site:
S96
Identified Species:
55.38
UniProt:
Q9NPD3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPD3
NP_061910.1
245
26383
S96
R
P
H
G
D
R
K
S
C
E
M
G
L
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539207
245
26416
S96
R
P
H
G
D
R
K
S
C
E
M
G
L
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q921I9
245
26231
S96
R
P
H
G
D
R
K
S
C
E
M
G
L
Q
L
Rat
Rattus norvegicus
NP_001128332
245
26372
S96
R
P
H
G
D
R
K
S
C
E
M
G
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515504
245
26566
A96
R
P
H
G
D
R
K
A
T
E
M
S
Q
H
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088679
249
27385
S96
R
P
H
G
D
R
K
S
S
E
M
T
L
H
L
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
D116
I
Q
G
S
E
E
R
D
L
S
A
T
L
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609618
246
27003
S92
R
P
R
G
D
R
K
S
L
E
F
K
L
Y
L
Honey Bee
Apis mellifera
XP_395806
268
29368
S101
K
P
R
G
D
R
K
S
Q
E
R
S
L
Q
L
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
S91
R
T
R
G
D
R
K
S
T
E
I
S
R
L
L
Sea Urchin
Strong. purpuratus
XP_785829
192
21229
I69
Y
P
R
S
Q
I
D
I
F
V
Q
I
L
Q
A
Poplar Tree
Populus trichocarpa
XP_002320845
241
26549
S92
K
P
K
G
D
R
R
S
T
E
I
S
L
V
I
Maize
Zea mays
NP_001131612
242
26471
S94
K
P
K
G
D
R
R
S
T
E
I
S
L
V
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46948
246
27542
V97
S
H
K
N
E
R
R
V
L
E
I
Q
T
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.9
N.A.
95.9
97.5
N.A.
84.9
N.A.
79.5
30.2
N.A.
52.4
46.6
43.6
46.1
Protein Similarity:
100
N.A.
N.A.
99.1
N.A.
98.7
100
N.A.
92.6
N.A.
90.3
45.7
N.A.
69.9
60.8
63.2
63.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
66.6
N.A.
80
6.6
N.A.
66.6
66.6
53.3
20
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
73.3
N.A.
80
20
N.A.
66.6
73.3
60
20
Percent
Protein Identity:
49.8
47.3
N.A.
N.A.
34.9
N.A.
Protein Similarity:
71.8
67.7
N.A.
N.A.
56.1
N.A.
P-Site Identity:
46.6
46.6
N.A.
N.A.
20
N.A.
P-Site Similarity:
73.3
73.3
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
79
0
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
15
8
0
0
0
86
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
8
79
0
0
0
0
0
0
0
29
0
0
0
% G
% His:
0
8
43
0
0
0
0
0
0
0
0
0
0
22
0
% H
% Ile:
8
0
0
0
0
8
0
8
0
0
29
8
0
0
15
% I
% Lys:
22
0
22
0
0
0
65
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
22
0
0
0
79
8
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
43
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
79
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
8
0
8
8
8
36
0
% Q
% Arg:
58
0
29
0
0
86
29
0
0
0
8
0
8
0
0
% R
% Ser:
8
0
0
15
0
0
0
72
8
8
0
36
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
29
0
0
15
8
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
8
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _