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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC4
All Species:
28.48
Human Site:
T80
Identified Species:
48.21
UniProt:
Q9NPD3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPD3
NP_061910.1
245
26383
T80
N
C
Q
Y
S
S
A
T
F
S
T
G
E
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539207
245
26416
T80
N
C
Q
Y
S
S
A
T
F
S
T
G
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q921I9
245
26231
T80
N
C
Q
Y
S
S
A
T
F
S
T
G
E
R
K
Rat
Rattus norvegicus
NP_001128332
245
26372
T80
N
C
Q
Y
S
S
A
T
F
S
T
G
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515504
245
26566
T80
N
C
Q
F
S
M
A
T
F
S
T
G
E
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088679
249
27385
T80
N
C
Q
Y
S
M
A
T
F
S
T
G
E
R
K
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
F100
C
D
F
R
L
A
P
F
S
C
V
K
R
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609618
246
27003
T76
N
C
Q
Y
S
Q
A
T
F
S
T
A
E
R
K
Honey Bee
Apis mellifera
XP_395806
268
29368
S85
Q
Y
S
M
A
V
F
S
L
S
S
G
E
R
K
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
K75
V
C
Q
Y
S
A
T
K
F
S
G
L
E
R
K
Sea Urchin
Strong. purpuratus
XP_785829
192
21229
F53
S
L
H
L
Q
R
T
F
E
A
T
I
Q
T
H
Poplar Tree
Populus trichocarpa
XP_002320845
241
26549
N76
R
C
E
Y
S
M
A
N
F
S
T
G
D
R
R
Maize
Zea mays
NP_001131612
242
26471
E78
R
C
E
Y
R
M
A
E
F
S
T
G
D
R
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46948
246
27542
F81
V
S
V
N
I
T
K
F
S
K
F
E
R
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.9
N.A.
95.9
97.5
N.A.
84.9
N.A.
79.5
30.2
N.A.
52.4
46.6
43.6
46.1
Protein Similarity:
100
N.A.
N.A.
99.1
N.A.
98.7
100
N.A.
92.6
N.A.
90.3
45.7
N.A.
69.9
60.8
63.2
63.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
86.6
N.A.
93.3
0
N.A.
86.6
33.3
60
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
6.6
N.A.
86.6
53.3
66.6
26.6
Percent
Protein Identity:
49.8
47.3
N.A.
N.A.
34.9
N.A.
Protein Similarity:
71.8
67.7
N.A.
N.A.
56.1
N.A.
P-Site Identity:
60
53.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
80
73.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
65
0
0
8
0
8
0
0
8
% A
% Cys:
8
72
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
0
15
0
0
0
0
8
8
0
0
8
65
0
0
% E
% Phe:
0
0
8
8
0
0
8
22
72
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
65
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
8
0
8
0
0
72
% K
% Leu:
0
8
0
8
8
0
0
0
8
0
0
8
0
0
0
% L
% Met:
0
0
0
8
0
29
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
58
0
8
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
15
0
0
8
8
8
0
0
0
0
0
0
15
79
15
% R
% Ser:
8
8
8
0
65
29
0
8
15
79
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
15
50
0
0
72
0
0
8
0
% T
% Val:
15
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
65
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _