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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DMAP1 All Species: 23.64
Human Site: S457 Identified Species: 34.67
UniProt: Q9NPF5 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPF5 NP_001029195.1 467 52993 S457 K R R E S A S S S S S V K K A
Chimpanzee Pan troglodytes XP_513103 672 74885 S662 K R R E S A S S S S S V K K A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532609 501 56456 S490 R K R R E S A S S S S S V K K
Cat Felis silvestris
Mouse Mus musculus Q9JI44 468 53111 S458 K R R E S A S S S S S V K K A
Rat Rattus norvegicus NP_001015006 468 53155 S457 R K R R E S A S S S S S V K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422417 512 58586 E501 R R K V V G A E Q G A L R S P
Frog Xenopus laevis NP_001087876 464 53153 S454 K R R E S A S S S S S V K K M
Zebra Danio Brachydanio rerio NP_956549 464 53441 S454 K R R E S A S S S S S I K K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611503 433 50230 K424 P P S L V P I K T E A L D N S
Honey Bee Apis mellifera XP_392117 440 50974 G431 A D I I D V V G S P S M P S I
Nematode Worm Caenorhab. elegans NP_740945 486 55822 N470 S S F V S S S N S P S T S A A
Sea Urchin Strong. purpuratus XP_001197869 455 52143 Q446 K R L A A V E Q G N V L K K L
Poplar Tree Populus trichocarpa XP_002320280 443 49457 A431 S E N P S S P A H K R P R K L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850470 441 49805 P426 P G R Q A D T P S P A H K R P
Baker's Yeast Sacchar. cerevisiae P53201 476 55194 K454 R Q E E L L K K I N T L I D L
Red Bread Mold Neurospora crassa Q870Q1 733 80376 L720 H K R S A S V L S N A S D K S
Conservation
Percent
Protein Identity: 100 69.4 N.A. 92.8 N.A. 97.8 98.2 N.A. N.A. 76.5 83 79.8 N.A. 47.1 53.7 38 51.8
Protein Similarity: 100 69.4 N.A. 92.8 N.A. 98 98.7 N.A. N.A. 81 89.9 86.9 N.A. 67 68.3 55.9 64.8
P-Site Identity: 100 100 N.A. 40 N.A. 100 40 N.A. N.A. 6.6 93.3 86.6 N.A. 0 13.3 33.3 26.6
P-Site Similarity: 100 100 N.A. 66.6 N.A. 100 66.6 N.A. N.A. 46.6 93.3 93.3 N.A. 26.6 20 46.6 46.6
Percent
Protein Identity: 30.1 N.A. N.A. 26.9 21.4 22.2
Protein Similarity: 46.2 N.A. N.A. 44.7 41.3 34.9
P-Site Identity: 13.3 N.A. N.A. 20 6.6 20
P-Site Similarity: 33.3 N.A. N.A. 53.3 40 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 19 32 19 7 0 0 25 0 0 7 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 7 0 0 0 0 0 0 13 7 0 % D
% Glu: 0 7 7 38 13 0 7 7 0 7 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 7 0 7 7 7 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % H
% Ile: 0 0 7 7 0 0 7 0 7 0 0 7 7 0 7 % I
% Lys: 38 19 7 0 0 0 7 13 0 7 0 0 44 63 13 % K
% Leu: 0 0 7 7 7 7 0 7 0 0 0 25 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % M
% Asn: 0 0 7 0 0 0 0 7 0 19 0 0 0 7 0 % N
% Pro: 13 7 0 7 0 7 7 7 0 19 0 7 7 0 13 % P
% Gln: 0 7 0 7 0 0 0 7 7 0 0 0 0 0 0 % Q
% Arg: 25 44 57 13 0 0 0 0 0 0 7 0 13 7 0 % R
% Ser: 13 7 7 7 44 32 38 44 69 44 57 19 7 13 13 % S
% Thr: 0 0 0 0 0 0 7 0 7 0 7 7 0 0 0 % T
% Val: 0 0 0 13 13 13 13 0 0 0 7 25 13 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _