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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAP2
All Species:
33.64
Human Site:
Y289
Identified Species:
61.67
UniProt:
Q9NPF8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPF8
NP_060874.1
381
44349
Y289
C
H
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Chimpanzee
Pan troglodytes
XP_001174772
381
44399
Y289
C
H
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Rhesus Macaque
Macaca mulatta
XP_001112623
381
44424
Y289
C
H
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Dog
Lupus familis
XP_853426
476
54458
Y289
P
Q
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2V5
381
43971
Y289
P
Q
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Rat
Rattus norvegicus
Q9JK15
376
43505
Y288
P
Q
E
R
R
L
L
Y
Y
K
N
P
L
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511195
425
48426
Y324
H
T
R
N
L
F
V
Y
H
E
S
G
K
E
I
Chicken
Gallus gallus
Q5F413
428
46296
Y291
M
A
P
A
Q
M
A
Y
P
A
A
A
Y
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661215
378
44463
Y288
S
M
D
R
K
L
L
Y
F
K
T
Q
L
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624178
375
43097
Y284
L
D
G
R
K
L
M
Y
H
D
D
P
M
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783514
333
39292
Y245
L
D
G
R
L
L
S
Y
Y
S
D
P
L
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FVJ3
337
37127
F247
G
S
V
K
L
Q
V
F
D
Y
D
T
F
S
A
Baker's Yeast
Sacchar. cerevisiae
P40529
298
32620
T215
I
G
A
A
N
T
K
T
G
N
R
V
G
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96
71.6
N.A.
84.5
83.1
N.A.
53.1
21.9
N.A.
56.9
N.A.
N.A.
41.7
N.A.
36.7
Protein Similarity:
100
100
98.1
75.8
N.A.
93.1
92.9
N.A.
61.6
40.6
N.A.
72.6
N.A.
N.A.
63.2
N.A.
55.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
6.6
6.6
N.A.
53.3
N.A.
N.A.
40
N.A.
53.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
40
26.6
N.A.
73.3
N.A.
N.A.
73.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.4
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.7
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
16
0
0
8
0
0
8
8
8
0
0
77
% A
% Cys:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
0
0
0
0
0
8
8
24
0
0
70
0
% D
% Glu:
0
0
47
0
0
0
0
0
0
8
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
8
0
8
8
0
0
0
8
0
8
% F
% Gly:
8
8
16
0
0
0
0
0
8
0
0
8
8
0
0
% G
% His:
8
24
0
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
16
0
8
0
0
54
0
0
8
0
0
% K
% Leu:
16
0
0
0
24
70
54
0
0
0
0
0
62
0
0
% L
% Met:
8
8
0
0
0
8
8
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
8
47
0
0
0
0
% N
% Pro:
24
0
8
0
0
0
0
0
8
0
0
62
0
0
0
% P
% Gln:
0
24
0
0
8
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
70
47
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
8
0
0
8
8
0
0
8
8
% S
% Thr:
0
8
0
0
0
8
0
8
0
0
8
8
0
8
0
% T
% Val:
0
0
8
0
0
0
16
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
54
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _