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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD3
All Species:
31.82
Human Site:
S548
Identified Species:
70
UniProt:
Q9NPG1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPG1
NP_059108.1
666
76263
S548
N
T
P
I
I
R
K
S
R
G
T
S
T
Q
G
Chimpanzee
Pan troglodytes
XP_001166266
673
76950
S555
N
T
P
I
I
R
K
S
R
G
T
S
T
Q
G
Rhesus Macaque
Macaca mulatta
XP_001110867
666
76218
S548
N
T
P
I
I
R
K
S
R
G
T
S
T
Q
G
Dog
Lupus familis
XP_543219
666
76260
S548
N
T
P
I
I
R
K
S
R
G
T
S
T
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61086
666
76189
S548
N
T
P
I
I
R
K
S
R
G
T
S
T
Q
G
Rat
Rattus norvegicus
Q08463
641
71009
L524
D
G
T
K
T
E
K
L
E
K
L
M
V
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516249
731
82006
S548
N
T
P
V
I
R
K
S
R
G
T
S
T
Q
G
Chicken
Gallus gallus
O57329
567
62793
H450
R
I
R
T
I
M
K
H
D
G
T
K
T
E
K
Frog
Xenopus laevis
O42579
664
75600
S547
N
T
P
I
V
R
K
S
R
G
T
S
T
Q
G
Zebra Danio
Brachydanio rerio
NP_001036226
685
77473
S550
N
T
P
V
V
R
K
S
R
G
T
S
T
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
K464
T
D
G
K
R
T
D
K
L
E
R
L
M
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
99.4
98.1
N.A.
98.1
38.4
N.A.
78.3
39.6
89
74.1
N.A.
33.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
99.8
99.5
N.A.
99.2
54.2
N.A.
84.6
53.5
94.5
84.8
N.A.
48.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
33.3
93.3
86.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
40
100
100
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
10
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
82
0
0
0
0
73
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
55
64
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
19
0
0
91
10
0
10
0
10
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
10
10
0
10
10
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% M
% Asn:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
0
% Q
% Arg:
10
0
10
0
10
73
0
0
73
0
10
0
0
10
10
% R
% Ser:
0
0
0
0
0
0
0
73
0
0
0
73
0
0
0
% S
% Thr:
10
73
10
10
10
10
0
0
0
0
82
0
82
0
0
% T
% Val:
0
0
0
19
19
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _