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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD3 All Species: 25.15
Human Site: T618 Identified Species: 55.33
UniProt: Q9NPG1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPG1 NP_059108.1 666 76263 T618 H G S M S R L T D H S R H S S
Chimpanzee Pan troglodytes XP_001166266 673 76950 T625 H G S M S R L T D H S R H S S
Rhesus Macaque Macaca mulatta XP_001110867 666 76218 T618 H G S M S R L T D H S R H S S
Dog Lupus familis XP_543219 666 76260 T618 H G S M S R L T D H S R H S S
Cat Felis silvestris
Mouse Mus musculus Q61086 666 76189 T618 H G S M S R L T D H S R H S S
Rat Rattus norvegicus Q08463 641 71009 F594 H P P M S P D F T V F M I K Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516249 731 82006 T618 D G H T S R L T D L S L P G S
Chicken Gallus gallus O57329 567 62793 F520 F A P M S P D F T V F M I K Y
Frog Xenopus laevis O42579 664 75600 T617 H G S M S H L T D H S R H S S
Zebra Danio Brachydanio rerio NP_001036226 685 77473 S620 E R V S H G S S L R L N E P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18537 581 64829 F534 A R P I F Q I F M V K Y L C S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 99.4 98.1 N.A. 98.1 38.4 N.A. 78.3 39.6 89 74.1 N.A. 33.9 N.A. N.A. N.A.
Protein Similarity: 100 98.2 99.8 99.5 N.A. 99.2 54.2 N.A. 84.6 53.5 94.5 84.8 N.A. 48.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 53.3 13.3 93.3 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 53.3 13.3 93.3 6.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 0 0 0 19 0 64 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 10 0 0 0 10 0 0 28 0 0 19 0 0 0 0 % F
% Gly: 0 64 0 0 0 10 0 0 0 0 0 0 0 10 0 % G
% His: 64 0 10 0 10 10 0 0 0 55 0 0 55 0 0 % H
% Ile: 0 0 0 10 0 0 10 0 0 0 0 0 19 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 19 0 % K
% Leu: 0 0 0 0 0 0 64 0 10 10 10 10 10 0 10 % L
% Met: 0 0 0 73 0 0 0 0 10 0 0 19 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 28 0 0 19 0 0 0 0 0 0 10 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 19 0 0 0 55 0 0 0 10 0 55 0 0 0 % R
% Ser: 0 0 55 10 82 0 10 10 0 0 64 0 0 55 73 % S
% Thr: 0 0 0 10 0 0 0 64 19 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 28 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _