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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD3
All Species:
31.82
Human Site:
Y233
Identified Species:
70
UniProt:
Q9NPG1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPG1
NP_059108.1
666
76263
Y233
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Chimpanzee
Pan troglodytes
XP_001166266
673
76950
Y233
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Rhesus Macaque
Macaca mulatta
XP_001110867
666
76218
Y233
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Dog
Lupus familis
XP_543219
666
76260
Y233
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q61086
666
76189
Y233
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Rat
Rattus norvegicus
Q08463
641
71009
T226
E
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516249
731
82006
Y233
I
D
V
R
R
F
R
Y
P
E
R
P
I
I
F
Chicken
Gallus gallus
O57329
567
62793
H152
R
C
E
N
F
P
V
H
G
A
G
E
I
C
V
Frog
Xenopus laevis
O42579
664
75600
Y232
I
D
V
T
R
F
R
Y
P
E
R
P
I
I
F
Zebra Danio
Brachydanio rerio
NP_001036226
685
77473
Y235
I
D
V
G
R
F
R
Y
P
E
R
P
I
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
E166
G
E
D
L
C
V
A
E
N
T
T
S
S
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
99.4
98.1
N.A.
98.1
38.4
N.A.
78.3
39.6
89
74.1
N.A.
33.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
99.8
99.5
N.A.
99.2
54.2
N.A.
84.6
53.5
94.5
84.8
N.A.
48.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
6.6
100
93.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
13.3
100
93.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% A
% Cys:
0
10
10
0
10
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
73
10
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
10
10
0
0
0
0
10
0
73
0
10
0
0
0
% E
% Phe:
0
0
0
0
10
73
0
0
0
0
0
0
0
0
73
% F
% Gly:
10
0
0
10
10
0
0
0
10
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
73
0
0
0
0
0
0
0
0
0
0
0
82
73
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
73
0
0
73
0
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
73
0
73
0
0
0
73
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
10
% S
% Thr:
0
0
0
55
0
0
0
10
0
10
10
0
10
0
10
% T
% Val:
0
0
73
10
0
10
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _