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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ISYNA1 All Species: 26.06
Human Site: S86 Identified Species: 47.78
UniProt: Q9NPH2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPH2 NP_057452.1 558 61068 S86 L A N R L R L S W P T R S G R
Chimpanzee Pan troglodytes XP_512514 399 43278
Rhesus Macaque Macaca mulatta XP_001114550 559 61010 S86 L A N R L R L S W P T R S G R
Dog Lupus familis XP_533872 557 60721 S86 L A N R L R L S W P T R T G R
Cat Felis silvestris
Mouse Mus musculus Q9JHU9 557 60913 T86 L A N R L R L T W P T R T G R
Rat Rattus norvegicus Q6AYK3 557 60865 T86 L A N R L R L T W P T R T G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DDT1 563 62365 S84 L A N R L G L S W M T K T G K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97477 565 62231 K89 E A N R R Q L K W R K R T G V
Honey Bee Apis mellifera XP_623542 512 57043 T84 L A N K L K L T W D T K N G I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307107 510 56397 G80 N G S T L T G G V I A N R E G
Maize Zea mays Q9FPK7 510 56227 G80 N G S T L T A G V I A N R E G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LX12 510 56399 R85 T A G V I A N R E G I S W A T
Baker's Yeast Sacchar. cerevisiae P11986 533 59624 E93 L A N K H N V E F Q T K E G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.3 97.8 92.4 N.A. 88.3 88.7 N.A. N.A. N.A. 69.8 N.A. N.A. 58.5 59.6 N.A. N.A.
Protein Similarity: 100 71.5 98.3 95.1 N.A. 92.4 93.5 N.A. N.A. N.A. 82.4 N.A. N.A. 72.9 75.4 N.A. N.A.
P-Site Identity: 100 0 100 93.3 N.A. 86.6 86.6 N.A. N.A. N.A. 66.6 N.A. N.A. 46.6 53.3 N.A. N.A.
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 N.A. N.A. 60 86.6 N.A. N.A.
Percent
Protein Identity: 55.3 56.8 N.A. 55.2 46.5 N.A.
Protein Similarity: 70.6 72.4 N.A. 71.3 66.3 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 33.3 N.A.
P-Site Similarity: 13.3 13.3 N.A. 13.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 77 0 0 0 8 8 0 0 0 16 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 8 8 0 0 0 8 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 16 8 0 0 8 8 16 0 8 0 0 0 70 16 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 16 8 0 0 0 8 % I
% Lys: 0 0 0 16 0 8 0 8 0 0 8 24 0 0 8 % K
% Leu: 62 0 0 0 70 0 62 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 16 0 70 0 0 8 8 0 0 0 0 16 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 54 8 39 0 8 0 8 0 47 16 0 39 % R
% Ser: 0 0 16 0 0 0 0 31 0 0 0 8 16 0 0 % S
% Thr: 8 0 0 16 0 16 0 24 0 0 62 0 39 0 8 % T
% Val: 0 0 0 8 0 0 8 0 16 0 0 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 62 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _