KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISYNA1
All Species:
25.76
Human Site:
Y371
Identified Species:
47.22
UniProt:
Q9NPH2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPH2
NP_057452.1
558
61068
Y371
V
Q
S
N
P
V
L
Y
T
P
G
E
E
P
D
Chimpanzee
Pan troglodytes
XP_512514
399
43278
P228
C
V
V
I
K
Y
V
P
Y
V
G
D
S
K
R
Rhesus Macaque
Macaca mulatta
XP_001114550
559
61010
Y371
V
Q
S
N
P
V
L
Y
A
P
G
E
E
P
D
Dog
Lupus familis
XP_533872
557
60721
Y371
V
Q
S
N
P
V
L
Y
A
P
G
E
E
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHU9
557
60913
Y371
V
H
S
N
H
V
L
Y
A
P
G
E
R
P
D
Rat
Rattus norvegicus
Q6AYK3
557
60865
Y371
V
Q
S
N
R
V
L
Y
A
P
G
E
E
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DDT1
563
62365
Y368
V
Q
S
N
P
I
L
Y
G
P
N
E
K
P
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97477
565
62231
Y375
V
A
S
N
R
L
L
Y
G
P
D
E
H
P
D
Honey Bee
Apis mellifera
XP_623542
512
57043
N340
L
G
N
N
D
G
Y
N
L
S
A
P
Q
Q
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307107
510
56397
S334
I
K
P
T
S
I
V
S
Y
N
H
L
G
N
N
Maize
Zea mays
Q9FPK7
510
56227
S334
I
K
P
T
S
I
V
S
Y
N
H
L
G
N
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX12
510
56399
L338
S
I
V
S
Y
N
H
L
G
N
N
D
G
M
N
Baker's Yeast
Sacchar. cerevisiae
P11986
533
59624
N359
L
G
N
N
D
G
Y
N
L
S
A
P
K
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.3
97.8
92.4
N.A.
88.3
88.7
N.A.
N.A.
N.A.
69.8
N.A.
N.A.
58.5
59.6
N.A.
N.A.
Protein Similarity:
100
71.5
98.3
95.1
N.A.
92.4
93.5
N.A.
N.A.
N.A.
82.4
N.A.
N.A.
72.9
75.4
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
73.3
86.6
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
60
6.6
N.A.
N.A.
P-Site Similarity:
100
20
93.3
93.3
N.A.
73.3
86.6
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
66.6
26.6
N.A.
N.A.
Percent
Protein Identity:
55.3
56.8
N.A.
55.2
46.5
N.A.
Protein Similarity:
70.6
72.4
N.A.
71.3
66.3
N.A.
P-Site Identity:
0
0
N.A.
0
6.6
N.A.
P-Site Similarity:
33.3
33.3
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
31
0
16
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
0
8
16
0
0
54
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
54
31
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
16
0
0
0
16
0
0
24
0
47
0
24
0
0
% G
% His:
0
8
0
0
8
0
8
0
0
0
16
0
8
0
0
% H
% Ile:
16
8
0
8
0
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
16
0
0
8
0
0
0
0
0
0
0
16
8
0
% K
% Leu:
16
0
0
0
0
8
54
8
16
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
16
70
0
8
0
16
0
24
16
0
0
16
24
% N
% Pro:
0
0
16
0
31
0
0
8
0
54
0
16
0
54
0
% P
% Gln:
0
39
0
0
0
0
0
0
0
0
0
0
8
16
0
% Q
% Arg:
0
0
0
0
16
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
8
0
54
8
16
0
0
16
0
16
0
0
8
0
0
% S
% Thr:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
54
8
16
0
0
39
24
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
16
54
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _