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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL1RAP
All Species:
18.18
Human Site:
S456
Identified Species:
66.67
UniProt:
Q9NPH3
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPH3
NP_002173.1
570
65418
S456
I
V
T
D
E
T
L
S
F
I
Q
K
S
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
P59822
570
65375
S456
I
V
T
D
E
T
L
S
F
I
Q
K
S
R
R
Dog
Lupus familis
XP_545250
634
72318
S520
I
V
T
D
E
T
L
S
F
I
Q
K
S
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61730
570
65722
S456
I
V
T
D
E
T
L
S
F
I
Q
K
S
R
R
Rat
Rattus norvegicus
Q63621
570
65580
S456
I
V
T
D
E
T
L
S
F
I
Q
K
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512445
670
76388
D439
N
T
V
E
A
V
F
D
F
I
Q
R
S
R
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B6ZK77
700
80295
R465
T
Y
I
E
D
V
A
R
C
V
D
Q
S
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
75.3
N.A.
89.1
88.9
N.A.
54.9
N.A.
N.A.
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.4
80.1
N.A.
95
94.5
N.A.
67
N.A.
N.A.
46.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
40
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
53.3
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
15
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
0
72
15
0
0
15
0
0
15
0
0
0
0
% D
% Glu:
0
0
0
29
72
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
86
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
72
0
15
0
0
0
0
0
0
86
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
72
0
15
0
% K
% Leu:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
86
15
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
15
0
0
0
15
0
86
100
% R
% Ser:
0
0
0
0
0
0
0
72
0
0
0
0
100
0
0
% S
% Thr:
15
15
72
0
0
72
0
0
0
0
0
0
0
0
0
% T
% Val:
0
72
15
0
0
29
0
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _