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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOX4
All Species:
17.58
Human Site:
S238
Identified Species:
35.15
UniProt:
Q9NPH5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPH5
NP_001137308.1
578
66932
S238
R
T
S
S
Q
N
I
S
L
P
E
Y
F
S
E
Chimpanzee
Pan troglodytes
XP_001136540
578
67008
S238
R
T
S
S
Q
N
I
S
L
P
E
Y
F
S
E
Rhesus Macaque
Macaca mulatta
XP_001105410
578
67002
S238
R
T
S
S
Q
N
I
S
L
P
E
Y
F
P
E
Dog
Lupus familis
XP_542262
584
67509
H242
G
T
R
Y
Q
N
I
H
L
P
N
Y
R
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI8
578
66501
S238
Q
T
S
S
Q
N
M
S
I
P
D
Y
V
S
E
Rat
Rattus norvegicus
Q924V1
578
66451
S238
R
T
P
S
Q
N
M
S
I
A
D
Y
V
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512272
560
64714
Y237
P
K
P
F
P
E
R
Y
G
K
S
E
P
L
I
Chicken
Gallus gallus
NP_001095299
541
62762
Y223
I
S
G
P
L
C
L
Y
C
V
E
R
L
Y
R
Frog
Xenopus laevis
NP_001085924
570
64842
R236
R
G
Q
T
A
A
S
R
E
K
H
N
P
R
D
Zebra Danio
Brachydanio rerio
NP_956708
565
64471
H236
T
D
A
D
L
Q
V
H
D
P
T
I
C
H
S
Tiger Blowfish
Takifugu rubipres
NP_001027904
565
64536
N236
T
P
A
S
L
K
S
N
D
P
T
V
C
A
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SW17
863
98576
G447
K
S
T
E
G
I
T
G
L
V
M
V
F
L
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
86.1
N.A.
90.6
89.9
N.A.
81.3
69.3
35.1
38.2
36.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.6
90.5
N.A.
96.1
95.5
N.A.
88.5
78.1
53.1
55.8
56.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
66.6
60
N.A.
0
6.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
60
N.A.
93.3
80
N.A.
0
20
20
20
40
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
9
0
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
17
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
17
0
17
0
0
0
17
% D
% Glu:
0
0
0
9
0
9
0
0
9
0
34
9
0
0
50
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
34
0
0
% F
% Gly:
9
9
9
0
9
0
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
9
0
0
9
0
% H
% Ile:
9
0
0
0
0
9
34
0
17
0
0
9
0
0
9
% I
% Lys:
9
9
0
0
0
9
0
0
0
17
0
0
0
0
0
% K
% Leu:
0
0
0
0
25
0
9
0
42
0
0
0
9
17
0
% L
% Met:
0
0
0
0
0
0
17
0
0
0
9
0
0
0
9
% M
% Asn:
0
0
0
0
0
50
0
9
0
0
9
9
0
0
0
% N
% Pro:
9
9
17
9
9
0
0
0
0
59
0
0
17
9
0
% P
% Gln:
9
0
9
0
50
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
42
0
9
0
0
0
9
9
0
0
0
9
9
9
9
% R
% Ser:
0
17
34
50
0
0
17
42
0
0
9
0
0
42
9
% S
% Thr:
17
50
9
9
0
0
9
0
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
17
0
17
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
17
0
0
0
50
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _