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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOX4
All Species:
18.79
Human Site:
Y300
Identified Species:
37.58
UniProt:
Q9NPH5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPH5
NP_001137308.1
578
66932
Y300
L
Y
C
A
E
R
L
Y
R
Y
I
R
S
N
K
Chimpanzee
Pan troglodytes
XP_001136540
578
67008
Y300
L
Y
C
A
E
R
L
Y
R
Y
I
R
S
N
K
Rhesus Macaque
Macaca mulatta
XP_001105410
578
67002
Y300
L
Y
C
A
E
R
L
Y
R
Y
I
R
S
N
K
Dog
Lupus familis
XP_542262
584
67509
T306
L
Y
C
D
T
C
F
T
S
V
K
L
N
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI8
578
66501
Y300
L
Y
C
A
E
R
L
Y
R
C
I
R
S
N
K
Rat
Rattus norvegicus
Q924V1
578
66451
Y300
L
Y
C
A
E
R
L
Y
R
C
I
R
S
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512272
560
64714
I294
S
N
K
P
V
T
I
I
S
V
I
S
H
P
S
Chicken
Gallus gallus
NP_001095299
541
62762
E279
C
P
R
V
S
G
L
E
S
H
P
F
T
L
T
Frog
Xenopus laevis
NP_001085924
570
64842
I297
R
S
Q
Q
K
V
V
I
T
K
V
V
T
H
P
Zebra Danio
Brachydanio rerio
NP_956708
565
64471
V293
F
Y
R
S
Q
Q
K
V
V
I
T
K
V
V
T
Tiger Blowfish
Takifugu rubipres
NP_001027904
565
64536
I295
R
S
H
Q
K
V
V
I
T
K
V
V
M
H
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SW17
863
98576
I536
L
Y
A
Y
E
R
L
I
R
A
F
R
S
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
86.1
N.A.
90.6
89.9
N.A.
81.3
69.3
35.1
38.2
36.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.6
90.5
N.A.
96.1
95.5
N.A.
88.5
78.1
53.1
55.8
56.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
93.3
93.3
N.A.
6.6
6.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
13.3
20
33.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
42
0
0
0
0
0
9
0
0
0
9
0
% A
% Cys:
9
0
50
0
0
9
0
0
0
17
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
50
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
9
0
0
9
17
0
% H
% Ile:
0
0
0
0
0
0
9
34
0
9
50
0
0
0
9
% I
% Lys:
0
0
9
0
17
0
9
0
0
17
9
9
0
0
42
% K
% Leu:
59
0
0
0
0
0
59
0
0
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
9
42
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
0
9
0
0
9
25
% P
% Gln:
0
0
9
17
9
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
17
0
0
50
0
0
50
0
0
50
0
0
0
% R
% Ser:
9
17
0
9
9
0
0
0
25
0
0
9
50
9
9
% S
% Thr:
0
0
0
0
9
9
0
9
17
0
9
0
17
0
17
% T
% Val:
0
0
0
9
9
17
17
9
9
17
17
17
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
9
0
0
0
42
0
25
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _