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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCF
All Species:
10
Human Site:
S132
Identified Species:
44
UniProt:
Q9NPI8
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPI8
NP_073562.1
374
42254
S132
D
E
E
T
L
Q
E
S
L
A
R
L
A
R
R
Chimpanzee
Pan troglodytes
XP_001169698
493
55821
S251
D
E
E
T
L
Q
E
S
L
A
R
L
A
R
R
Rhesus Macaque
Macaca mulatta
XP_001092387
619
68864
S377
D
E
E
T
L
Q
E
S
L
A
R
L
A
R
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001108559
343
38206
R122
R
D
D
V
P
Q
S
R
L
V
L
L
A
R
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234315
391
43000
A159
G
F
E
L
G
R
L
A
P
L
A
R
R
K
A
Frog
Xenopus laevis
NP_001086451
339
39009
Y108
L
S
R
N
I
F
Q
Y
I
V
T
K
L
K
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
56.8
N.A.
N.A.
48.6
N.A.
N.A.
N.A.
35
25.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.2
58.1
N.A.
N.A.
59.6
N.A.
N.A.
N.A.
48.3
47
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
50
17
0
67
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% C
% Asp:
50
17
17
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
67
0
0
0
50
0
0
0
0
0
0
0
0
% E
% Phe:
0
17
0
0
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
0
17
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
17
0
34
0
% K
% Leu:
17
0
0
17
50
0
17
0
67
17
17
67
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
17
% N
% Pro:
0
0
0
0
17
0
0
0
17
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
67
17
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
17
0
0
17
0
17
0
0
50
17
17
67
50
% R
% Ser:
0
17
0
0
0
0
17
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
50
0
0
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
34
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _