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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ16
All Species:
28.48
Human Site:
S227
Identified Species:
62.67
UniProt:
Q9NPI9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPI9
NP_061128.1
418
47949
S227
L
L
R
Y
T
E
D
S
E
G
R
M
T
M
A
Chimpanzee
Pan troglodytes
XP_523700
418
47945
S227
L
L
R
Y
T
E
D
S
E
G
R
M
T
M
A
Rhesus Macaque
Macaca mulatta
XP_001083604
418
47808
S227
L
L
R
Y
T
E
D
S
E
G
R
M
T
M
A
Dog
Lupus familis
XP_853764
419
47892
S227
L
L
R
Y
T
E
D
S
E
G
R
M
T
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z307
419
48003
S227
L
L
R
Y
S
E
D
S
E
G
R
M
T
M
A
Rat
Rattus norvegicus
P52191
419
47917
S227
L
L
R
Y
S
E
D
S
E
G
R
M
T
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509387
554
63083
S358
L
L
R
W
V
E
D
S
Q
G
R
M
T
M
E
Chicken
Gallus gallus
P52186
427
48500
S238
L
L
K
S
R
I
T
S
E
G
E
Y
I
P
L
Frog
Xenopus laevis
NP_001079187
412
46986
H223
L
V
R
Y
Y
E
D
H
E
K
G
I
T
M
E
Zebra Danio
Brachydanio rerio
XP_001923086
427
48469
A236
L
L
R
S
R
T
T
A
E
G
E
F
I
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
N269
F
I
T
D
R
E
T
N
E
G
E
I
E
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
95.6
N.A.
91.6
92.1
N.A.
62.8
44.9
63.8
41.9
N.A.
N.A.
N.A.
31
N.A.
Protein Similarity:
100
99.7
99
97.1
N.A.
94.9
95.4
N.A.
70.2
60.6
77.7
58.5
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
33.3
53.3
33.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
40
66.6
40
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
73
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
82
0
0
91
0
28
0
10
0
19
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
91
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
19
19
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
91
82
0
0
0
0
0
0
0
0
0
0
0
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
64
0
73
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
82
0
28
0
0
0
0
0
64
0
0
0
0
% R
% Ser:
0
0
0
19
19
0
0
73
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
37
10
28
0
0
0
0
0
73
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
64
10
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _