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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKKS
All Species:
19.09
Human Site:
S253
Identified Species:
60
UniProt:
Q9NPJ1
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPJ1
NP_061336.1
570
62342
S253
T
T
L
S
G
D
T
S
D
T
G
E
G
T
V
Chimpanzee
Pan troglodytes
XP_514516
570
62358
S253
T
T
L
S
G
D
I
S
D
T
G
E
G
T
V
Rhesus Macaque
Macaca mulatta
XP_001116181
570
62289
S253
T
T
L
S
G
D
I
S
D
T
G
E
G
T
V
Dog
Lupus familis
XP_542894
570
62157
S253
A
S
L
S
G
D
L
S
D
T
G
E
G
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI70
570
61933
S253
T
S
L
S
G
D
F
S
N
A
G
E
G
V
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513856
573
62330
D253
F
C
V
S
M
A
G
D
L
S
D
V
G
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956459
563
61520
S253
V
S
L
S
G
D
I
S
E
V
G
D
V
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786835
667
72376
F308
G
C
I
R
V
V
L
F
N
I
S
L
S
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.3
83.6
N.A.
77
N.A.
N.A.
67.8
N.A.
N.A.
42.2
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
99.3
98.7
91.7
N.A.
87.7
N.A.
N.A.
80.8
N.A.
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
45.4
P-Site Identity:
100
93.3
93.3
73.3
N.A.
66.6
N.A.
N.A.
13.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
80
N.A.
N.A.
26.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
13
0
0
0
13
0
0
0
13
0
% A
% Cys:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
75
0
13
50
0
13
13
0
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
13
0
0
63
0
13
0
% E
% Phe:
13
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
75
0
13
0
0
0
75
0
75
13
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
0
38
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
75
0
0
0
25
0
13
0
0
13
0
0
13
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
38
0
88
0
0
0
75
0
13
13
0
13
0
0
% S
% Thr:
50
38
0
0
0
0
13
0
0
50
0
0
0
50
0
% T
% Val:
13
0
13
0
13
13
0
0
0
13
0
13
13
13
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _