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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKKS
All Species:
16.36
Human Site:
S533
Identified Species:
51.43
UniProt:
Q9NPJ1
Number Species:
7
Phosphosite Substitution
Charge Score:
0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPJ1
NP_061336.1
570
62342
S533
L
P
H
E
A
V
G
S
A
S
N
L
T
L
D
Chimpanzee
Pan troglodytes
XP_514516
570
62358
S533
L
P
H
E
A
V
G
S
A
S
N
L
I
L
D
Rhesus Macaque
Macaca mulatta
XP_001116181
570
62289
S533
L
P
L
E
A
V
G
S
A
S
N
L
T
L
D
Dog
Lupus familis
XP_542894
570
62157
S533
L
P
H
E
A
T
G
S
A
D
N
L
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI70
570
61933
S533
L
P
Q
A
A
L
G
S
A
S
N
L
T
V
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513856
573
62330
D535
C
H
S
Q
Q
A
L
D
S
V
D
Q
L
T
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956459
563
61520
D526
P
V
F
L
E
N
S
D
T
Q
P
K
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786835
667
72376
E584
M
E
K
Q
A
V
N
E
A
S
R
T
V
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.3
83.6
N.A.
77
N.A.
N.A.
67.8
N.A.
N.A.
42.2
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
99.3
98.7
91.7
N.A.
87.7
N.A.
N.A.
80.8
N.A.
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
45.4
P-Site Identity:
100
93.3
93.3
86.6
N.A.
73.3
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
86.6
N.A.
N.A.
20
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
75
13
0
0
75
0
0
0
0
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
25
0
13
13
0
0
0
88
% D
% Glu:
0
13
0
50
13
0
0
13
0
0
0
0
0
13
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
63
0
0
0
0
0
0
0
0
% G
% His:
0
13
38
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
13
0
0
0
% K
% Leu:
63
0
13
13
0
13
13
0
0
0
0
63
13
63
13
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
13
0
0
0
63
0
0
0
0
% N
% Pro:
13
63
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
13
25
13
0
0
0
0
13
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% R
% Ser:
0
0
13
0
0
0
13
63
13
63
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
13
0
0
13
0
0
13
50
13
0
% T
% Val:
0
13
0
0
0
50
0
0
0
13
0
0
25
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _