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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED4 All Species: 0
Human Site: S105 Identified Species: 0
UniProt: Q9NPJ6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPJ6 NP_054885.1 270 29745 S105 K E V E K R D S D I Q Q L Q K
Chimpanzee Pan troglodytes XP_001151408 248 28027
Rhesus Macaque Macaca mulatta XP_001100111 270 29757
Dog Lupus familis XP_534120 363 39725
Cat Felis silvestris
Mouse Mus musculus Q9CQA5 270 29763
Rat Rattus norvegicus Q561Q8 270 29807
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514128 248 27969
Chicken Gallus gallus XP_417054 261 28661
Frog Xenopus laevis Q5XG48 252 28037
Zebra Danio Brachydanio rerio Q561X3 254 28034
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VS38 258 28294
Honey Bee Apis mellifera XP_396963 255 28162
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781304 249 27006
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.6 99.6 71.6 N.A. 94.4 93.6 N.A. 82.2 86.3 78.8 77.4 N.A. 41.8 50 N.A. 47.4
Protein Similarity: 100 87.4 99.6 73.2 N.A. 97.4 97 N.A. 88.1 93.3 85.5 85.5 N.A. 59.6 67.4 N.A. 65.1
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 0 N.A. 0
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 100 0 0 0 0 0 0 % D
% Glu: 0 100 0 100 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % I
% Lys: 100 0 0 0 100 0 0 0 0 0 0 0 0 0 100 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 100 100 0 100 0 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _