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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NXT2 All Species: 30
Human Site: T117 Identified Species: 60
UniProt: Q9NPJ8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPJ8 NP_061168.2 142 16228 T117 F N Q N F L L T A Q S T P N N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098951 197 22546 T172 F N Q N F L L T A Q S T P N N
Dog Lupus familis XP_853019 142 16251 T117 F N Q N F L L T A Q S T P N N
Cat Felis silvestris
Mouse Mus musculus Q3UNA4 142 16238 T117 F N Q N F L L T A Q S T P N S
Rat Rattus norvegicus B2GV77 142 16347 T117 F N Q N F L L T A Q S T P N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507973 141 16130 T117 F N Q N F L L T A Q V T P T N
Chicken Gallus gallus Q5ZLH0 141 16144 T117 F N Q N F L L T A Q A T S N S
Frog Xenopus laevis NP_001079986 140 16153 S116 F N Q N F L L S L H A T P T N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3H8 133 15163 Q109 D Q Q L R K F Q Q T F I V T A
Honey Bee Apis mellifera XP_396823 138 15801 L113 K S F N Q S F L I A A M G D K
Nematode Worm Caenorhab. elegans Q9U757 137 15461 A112 V D G D S K R A F T Q T L L L
Sea Urchin Strong. purpuratus XP_001175916 136 15233 A112 G K G N F P F A Q N F V L T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 70.5 90.1 N.A. 87.3 87.3 N.A. 85.2 88 73.9 N.A. N.A. 42.2 47.1 28.8 54.2
Protein Similarity: 100 N.A. 71 97.1 N.A. 93.6 92.9 N.A. 91.5 94.3 85.2 N.A. N.A. 60.5 59.8 53.5 69.7
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 86.6 80 66.6 N.A. N.A. 6.6 6.6 6.6 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 86.6 93.3 80 N.A. N.A. 6.6 26.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 59 9 25 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 9 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 67 0 9 0 75 0 25 0 9 0 17 0 0 0 0 % F
% Gly: 9 0 17 0 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % I
% Lys: 9 9 0 0 0 17 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 9 0 67 67 9 9 0 0 0 17 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 67 0 84 0 0 0 0 0 9 0 0 0 50 42 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 0 0 59 0 0 % P
% Gln: 0 9 75 0 9 0 0 9 17 59 9 0 0 0 9 % Q
% Arg: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 9 9 0 9 0 0 42 0 9 0 25 % S
% Thr: 0 0 0 0 0 0 0 59 0 17 0 75 0 34 0 % T
% Val: 9 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _