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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NXT2
All Species:
28.48
Human Site:
Y26
Identified Species:
56.97
UniProt:
Q9NPJ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPJ8
NP_061168.2
142
16228
Y26
E
E
F
V
N
I
Y
Y
E
T
M
D
K
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098951
197
22546
Y81
E
E
F
V
N
I
Y
Y
E
T
M
D
K
R
R
Dog
Lupus familis
XP_853019
142
16251
Y26
E
E
F
V
N
I
Y
Y
E
T
M
D
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UNA4
142
16238
Y26
E
E
F
V
N
I
Y
Y
E
T
M
D
K
R
R
Rat
Rattus norvegicus
B2GV77
142
16347
Y26
E
E
F
V
N
I
Y
Y
E
T
M
D
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507973
141
16130
Y26
E
E
F
A
N
I
Y
Y
E
T
M
D
K
R
R
Chicken
Gallus gallus
Q5ZLH0
141
16144
Y26
E
E
F
V
N
I
Y
Y
E
T
M
D
K
R
R
Frog
Xenopus laevis
NP_001079986
140
16153
E26
E
F
V
N
L
Y
Y
E
T
I
D
K
R
R
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3H8
133
15163
Y23
A
D
T
F
T
R
L
Y
Y
A
S
V
D
N
R
Honey Bee
Apis mellifera
XP_396823
138
15801
S26
F
T
K
L
Y
Y
E
S
L
D
K
R
R
Y
L
Nematode Worm
Caenorhab. elegans
Q9U757
137
15461
V26
E
S
K
K
F
M
D
V
Y
Y
D
V
M
D
R
Sea Urchin
Strong. purpuratus
XP_001175916
136
15233
F26
G
E
Q
F
Y
K
V
F
Y
E
N
F
D
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
70.5
90.1
N.A.
87.3
87.3
N.A.
85.2
88
73.9
N.A.
N.A.
42.2
47.1
28.8
54.2
Protein Similarity:
100
N.A.
71
97.1
N.A.
93.6
92.9
N.A.
91.5
94.3
85.2
N.A.
N.A.
60.5
59.8
53.5
69.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
100
26.6
N.A.
N.A.
13.3
0
13.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
100
33.3
N.A.
N.A.
20
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
9
17
59
17
9
0
% D
% Glu:
75
67
0
0
0
0
9
9
59
9
0
0
0
0
0
% E
% Phe:
9
9
59
17
9
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
59
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
17
9
0
9
0
0
0
0
9
9
59
9
9
% K
% Leu:
0
0
0
9
9
0
9
0
9
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
59
0
9
0
0
% M
% Asn:
0
0
0
9
59
0
0
0
0
0
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
9
17
67
84
% R
% Ser:
0
9
0
0
0
0
0
9
0
0
9
0
0
0
0
% S
% Thr:
0
9
9
0
9
0
0
0
9
59
0
0
0
0
0
% T
% Val:
0
0
9
50
0
0
9
9
0
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
17
67
67
25
9
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _