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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NXT2 All Species: 25.76
Human Site: Y40 Identified Species: 51.52
UniProt: Q9NPJ8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPJ8 NP_061168.2 142 16228 Y40 R R A L T R L Y L D K A T L I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098951 197 22546 Y95 R R A L T R L Y L D K A T L I
Dog Lupus familis XP_853019 142 16251 Y40 R R A L T R L Y L E K A T L I
Cat Felis silvestris
Mouse Mus musculus Q3UNA4 142 16238 Y40 R H A L V R L Y L D K A T L I
Rat Rattus norvegicus B2GV77 142 16347 Y40 R H A L V R L Y L D K A T L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507973 141 16130 Y40 R R V L T R L Y L D K A T L V
Chicken Gallus gallus Q5ZLH0 141 16144 Y40 R R A L T R L Y L D K A T L I
Frog Xenopus laevis NP_001079986 140 16153 M40 R Q L T K L Y M D S A T L V W
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3H8 133 15163 L37 R R Q Q I G R L Y L D N A T L
Honey Bee Apis mellifera XP_396823 138 15801 D40 L I S R L Y L D T A T L I W N
Nematode Worm Caenorhab. elegans Q9U757 137 15461 F40 R K R E K I G F L Y T Q V S N
Sea Urchin Strong. purpuratus XP_001175916 136 15233 L40 K R T L L G K L Y L D S A T M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 70.5 90.1 N.A. 87.3 87.3 N.A. 85.2 88 73.9 N.A. N.A. 42.2 47.1 28.8 54.2
Protein Similarity: 100 N.A. 71 97.1 N.A. 93.6 92.9 N.A. 91.5 94.3 85.2 N.A. N.A. 60.5 59.8 53.5 69.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 86.6 N.A. 86.6 100 6.6 N.A. N.A. 13.3 6.6 13.3 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 86.6 86.6 N.A. 93.3 100 20 N.A. N.A. 20 13.3 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 0 0 0 0 0 9 9 59 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 9 50 17 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 17 9 0 0 0 0 0 0 0 0 % G
% His: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 9 0 0 0 0 0 0 9 0 50 % I
% Lys: 9 9 0 0 17 0 9 0 0 0 59 0 0 0 0 % K
% Leu: 9 0 9 67 17 9 67 17 67 17 0 9 9 59 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 17 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 9 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 84 59 9 9 0 59 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 0 0 0 0 0 9 0 9 0 9 0 % S
% Thr: 0 0 9 9 42 0 0 0 9 0 17 9 59 17 0 % T
% Val: 0 0 9 0 17 0 0 0 0 0 0 0 9 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % W
% Tyr: 0 0 0 0 0 9 9 59 17 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _