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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIC8A All Species: 27.27
Human Site: S298 Identified Species: 54.55
UniProt: Q9NPQ8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPQ8 NP_068751.4 530 59612 S298 T L E P H G D S T E F M G V N
Chimpanzee Pan troglodytes XP_001143336 530 59630 S298 T L E P H G D S T E F M G V N
Rhesus Macaque Macaca mulatta XP_001083920 528 59373 S296 T L E P H E D S V E F M G V N
Dog Lupus familis XP_848262 529 59468 S297 T L E P H K G S L E F L G A N
Cat Felis silvestris
Mouse Mus musculus Q3TIR3 530 59828 S298 A L E L H E G S L E F M G V N
Rat Rattus norvegicus Q80ZG1 529 59815 S298 A L E L H E G S L E F M G V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508465 507 56644 L305 L H S N A V N L L S N V P V S
Chicken Gallus gallus Q5ZL77 539 61485 S307 T P K V R P G S L E Y M G V N
Frog Xenopus laevis Q45TX8 539 61255 S307 T P K V E Q G S V E Y M G M N
Zebra Danio Brachydanio rerio Q642H7 548 61977 S311 M P K V Q Q G S I E Y M G V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W358 573 65583 S346 F E K R N V R S L D V L L R Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9GSX9 566 63429 K332 H L D K Q L T K V V A L L L N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 93 89.4 N.A. 88.1 86.5 N.A. 42.8 67.7 58.6 57.8 N.A. 31.9 N.A. 26.5 N.A.
Protein Similarity: 100 99.4 94.9 94.1 N.A. 93.7 92.2 N.A. 59.6 80.5 74.9 73.5 N.A. 50.6 N.A. 46.6 N.A.
P-Site Identity: 100 100 86.6 66.6 N.A. 66.6 66.6 N.A. 6.6 46.6 40 40 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 86.6 73.3 N.A. 66.6 66.6 N.A. 26.6 60 60 53.3 N.A. 33.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 9 0 0 0 0 0 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 25 0 0 9 0 0 0 0 0 % D
% Glu: 0 9 50 0 9 25 0 0 0 75 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % F
% Gly: 0 0 0 0 0 17 50 0 0 0 0 0 75 0 0 % G
% His: 9 9 0 0 50 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 34 9 0 9 0 9 0 0 0 0 0 0 0 % K
% Leu: 9 59 0 17 0 9 0 9 50 0 0 25 17 9 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 67 0 9 0 % M
% Asn: 0 0 0 9 9 0 9 0 0 0 9 0 0 0 84 % N
% Pro: 0 25 0 34 0 9 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 17 17 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 9 0 9 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 9 0 0 0 0 84 0 9 0 0 0 0 9 % S
% Thr: 50 0 0 0 0 0 9 0 17 0 0 0 0 0 0 % T
% Val: 0 0 0 25 0 17 0 0 25 9 9 9 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _