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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA4B All Species: 19.09
Human Site: S774 Identified Species: 46.67
UniProt: Q9NPR2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPR2 NP_064595 832 92193 S774 L N G L G P P S T P L D H R G
Chimpanzee Pan troglodytes XP_510590 967 105400 S909 L N G L G P P S T P L D H R G
Rhesus Macaque Macaca mulatta XP_001096618 1203 131331 S1145 L N G L G P P S T P L D H R G
Dog Lupus familis XP_545859 916 101239 S858 L N G V G P P S T P L D H R G
Cat Felis silvestris
Mouse Mus musculus Q62179 823 91374 S765 L N G V G P P S T P L D H R G
Rat Rattus norvegicus Q9Z143 776 84280 S719 P S G T T S Y S Q D P P S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90607 772 88849 N715 M Q L I N H P N L N T M D E F
Frog Xenopus laevis NP_001087062 835 93986 L761 N G M P A E S L P L N G T N V
Zebra Danio Brachydanio rerio Q9YHX4 766 85599 A709 Q N R H E D D A N Q V Q P Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24322 850 95478 R785 R S L G R A R R Q P P R H G I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.9 67.4 79.2 N.A. 83.6 36.2 N.A. N.A. 31.2 57.3 33.1 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 82.3 68.5 84.2 N.A. 90.6 50.9 N.A. N.A. 47.4 72.3 50.7 N.A. 45.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. N.A. 6.6 0 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. N.A. 26.6 0 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 0 10 0 50 10 0 0 % D
% Glu: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 60 10 50 0 0 0 0 0 0 10 0 10 50 % G
% His: 0 0 0 10 0 10 0 0 0 0 0 0 60 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 50 0 20 30 0 0 0 10 10 10 50 0 0 0 0 % L
% Met: 10 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 10 60 0 0 10 0 0 10 10 10 10 0 0 10 0 % N
% Pro: 10 0 0 10 0 50 60 0 10 60 20 10 10 10 0 % P
% Gln: 10 10 0 0 0 0 0 0 20 10 0 10 0 10 0 % Q
% Arg: 10 0 10 0 10 0 10 10 0 0 0 10 0 50 10 % R
% Ser: 0 20 0 0 0 10 10 60 0 0 0 0 10 0 10 % S
% Thr: 0 0 0 10 10 0 0 0 50 0 10 0 10 0 0 % T
% Val: 0 0 0 20 0 0 0 0 0 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _