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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR108
All Species:
3.94
Human Site:
S149
Identified Species:
8.67
UniProt:
Q9NPR9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPR9
NP_001073921.1
543
60633
S149
G
L
L
P
E
A
P
S
K
P
G
L
P
K
P
Chimpanzee
Pan troglodytes
XP_001164765
571
63953
E151
K
I
V
F
S
R
D
E
K
V
L
G
Q
S
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533931
593
66469
S207
G
L
L
P
E
V
P
S
E
P
G
P
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD0
569
63962
E175
V
I
H
P
S
P
T
E
M
S
A
V
K
E
N
Rat
Rattus norvegicus
Q6P6V6
577
64702
D182
K
M
S
A
V
K
E
D
Q
A
K
L
T
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507835
704
79232
A303
P
K
I
I
F
T
N
A
K
V
Y
Q
D
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088393
584
66184
K181
A
E
N
A
N
K
K
K
E
D
A
L
E
K
K
Zebra Danio
Brachydanio rerio
NP_001073515
543
61840
E146
V
P
P
K
K
S
E
E
V
Q
V
E
K
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6G5
378
42998
R10
M
V
V
C
S
N
L
R
R
P
G
H
V
G
A
Honey Bee
Apis mellifera
XP_001121399
577
66851
V148
P
N
R
F
S
D
A
V
L
F
P
R
R
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796821
610
68683
L208
G
E
K
G
Q
G
Q
L
E
I
E
K
D
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.3
N.A.
76.2
N.A.
80.1
79.3
N.A.
40.9
N.A.
46.5
50.2
N.A.
20
38.6
N.A.
37.5
Protein Similarity:
100
63.7
N.A.
83.3
N.A.
86.9
87.1
N.A.
54.2
N.A.
63.7
67.7
N.A.
31.3
54.5
N.A.
54.7
P-Site Identity:
100
6.6
N.A.
80
N.A.
6.6
13.3
N.A.
6.6
N.A.
13.3
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
20
N.A.
86.6
N.A.
26.6
26.6
N.A.
20
N.A.
20
13.3
N.A.
33.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
0
10
10
10
0
10
19
0
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
10
0
10
0
0
19
0
0
% D
% Glu:
0
19
0
0
19
0
19
28
28
0
10
10
10
10
0
% E
% Phe:
0
0
0
19
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
28
0
0
10
0
10
0
0
0
0
28
10
0
19
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
19
10
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
19
10
10
10
10
19
10
10
28
0
10
10
19
37
19
% K
% Leu:
0
19
19
0
0
0
10
10
10
0
10
28
0
10
0
% L
% Met:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
10
10
10
0
0
0
0
0
0
0
10
% N
% Pro:
19
10
10
28
0
10
19
0
0
28
10
10
19
10
28
% P
% Gln:
0
0
0
0
10
0
10
0
10
10
0
10
10
0
10
% Q
% Arg:
0
0
10
0
0
10
0
10
10
0
0
10
10
0
10
% R
% Ser:
0
0
10
0
37
10
0
19
0
10
0
0
0
10
10
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% T
% Val:
19
10
19
0
10
10
0
10
10
19
10
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _