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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR108 All Species: 0.91
Human Site: T136 Identified Species: 2
UniProt: Q9NPR9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPR9 NP_001073921.1 543 60633 T136 R K Y G E Q K T L F I F P G L
Chimpanzee Pan troglodytes XP_001164765 571 63953 A138 R V K S P P E A G T Q L P K I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533931 593 66469 K194 R R Y G D Q K K L F I S P G L
Cat Felis silvestris
Mouse Mus musculus Q91WD0 569 63962 T162 P K P D P A G T P K D N H V I
Rat Rattus norvegicus Q6P6V6 577 64702 I169 T P K D N H V I H P S P K K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507835 704 79232 E290 V K I K S P P E A G T Q L P K
Chicken Gallus gallus
Frog Xenopus laevis NP_001088393 584 66184 R168 P L P E K M S R R D T E V A E
Zebra Danio Brachydanio rerio NP_001073515 543 61840 F133 T S A E T G V F P K I M A V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V6G5 378 42998
Honey Bee Apis mellifera XP_001121399 577 66851 E135 S K I L I F R E K R D S F P N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796821 610 68683 P195 L D G A G L N P V K P G P G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.3 N.A. 76.2 N.A. 80.1 79.3 N.A. 40.9 N.A. 46.5 50.2 N.A. 20 38.6 N.A. 37.5
Protein Similarity: 100 63.7 N.A. 83.3 N.A. 86.9 87.1 N.A. 54.2 N.A. 63.7 67.7 N.A. 31.3 54.5 N.A. 54.7
P-Site Identity: 100 13.3 N.A. 73.3 N.A. 13.3 0 N.A. 6.6 N.A. 0 6.6 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 26.6 N.A. 86.6 N.A. 20 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 0 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 0 10 10 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 19 10 0 0 0 0 10 19 0 0 0 0 % D
% Glu: 0 0 0 19 10 0 10 19 0 0 0 10 0 0 19 % E
% Phe: 0 0 0 0 0 10 0 10 0 19 0 10 10 0 0 % F
% Gly: 0 0 10 19 10 10 10 0 10 10 0 10 0 28 0 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 0 10 0 0 % H
% Ile: 0 0 19 0 10 0 0 10 0 0 28 0 0 0 19 % I
% Lys: 0 37 19 10 10 0 19 10 10 28 0 0 10 19 10 % K
% Leu: 10 10 0 10 0 10 0 0 19 0 0 10 10 0 19 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 10 0 0 10 % N
% Pro: 19 10 19 0 19 19 10 10 19 10 10 10 37 19 10 % P
% Gln: 0 0 0 0 0 19 0 0 0 0 10 10 0 0 0 % Q
% Arg: 28 10 0 0 0 0 10 10 10 10 0 0 0 0 0 % R
% Ser: 10 10 0 10 10 0 10 0 0 0 10 19 0 0 0 % S
% Thr: 19 0 0 0 10 0 0 19 0 10 19 0 0 0 0 % T
% Val: 10 10 0 0 0 0 19 0 10 0 0 0 10 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _