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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR108
All Species:
27.88
Human Site:
Y395
Identified Species:
61.33
UniProt:
Q9NPR9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NPR9
NP_001073921.1
543
60633
Y395
R
E
E
G
A
S
D
Y
V
L
W
K
E
I
L
Chimpanzee
Pan troglodytes
XP_001164765
571
63953
Y397
T
E
E
G
T
T
E
Y
G
L
W
K
D
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533931
593
66469
E450
S
D
Y
R
L
W
K
E
I
L
F
L
V
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD0
569
63962
Y421
R
E
E
G
A
S
D
Y
G
L
W
K
E
I
L
Rat
Rattus norvegicus
Q6P6V6
577
64702
Y428
R
E
E
G
A
S
D
Y
G
L
W
K
E
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507835
704
79232
Y549
T
E
E
G
T
T
D
Y
G
L
W
K
D
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088393
584
66184
Y427
T
E
E
G
T
T
E
Y
G
L
W
K
D
I
L
Zebra Danio
Brachydanio rerio
NP_001073515
543
61840
Y390
T
E
E
G
S
S
E
Y
G
L
W
M
E
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6G5
378
42998
A250
G
I
G
V
Y
Q
D
A
I
N
L
C
I
E
K
Honey Bee
Apis mellifera
XP_001121399
577
66851
Y388
S
E
E
G
D
I
E
Y
K
T
W
R
D
V
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796821
610
68683
Y454
S
E
E
G
E
A
Q
Y
S
M
W
K
V
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.3
N.A.
76.2
N.A.
80.1
79.3
N.A.
40.9
N.A.
46.5
50.2
N.A.
20
38.6
N.A.
37.5
Protein Similarity:
100
63.7
N.A.
83.3
N.A.
86.9
87.1
N.A.
54.2
N.A.
63.7
67.7
N.A.
31.3
54.5
N.A.
54.7
P-Site Identity:
100
53.3
N.A.
13.3
N.A.
93.3
93.3
N.A.
60
N.A.
60
66.6
N.A.
6.6
33.3
N.A.
40
P-Site Similarity:
100
73.3
N.A.
33.3
N.A.
93.3
93.3
N.A.
73.3
N.A.
80
80
N.A.
13.3
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
10
0
46
0
0
0
0
0
37
10
0
% D
% Glu:
0
82
82
0
10
0
37
10
0
0
0
0
37
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
19
% F
% Gly:
10
0
10
82
0
0
0
0
55
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
19
0
0
0
10
46
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
0
0
64
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
0
73
10
10
0
0
73
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% Q
% Arg:
28
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
28
0
0
0
10
37
0
0
10
0
0
0
0
19
0
% S
% Thr:
37
0
0
0
28
28
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
0
19
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
82
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _