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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASCL3 All Species: 10.61
Human Site: S8 Identified Species: 19.44
UniProt: Q9NQ33 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ33 NP_065697.1 180 20797 S8 M D N R G N S S L P D K L P I
Chimpanzee Pan troglodytes XP_522303 181 20906 S9 M D N R G N S S L P D K L P I
Rhesus Macaque Macaca mulatta XP_001102401 181 20820 C9 M D N R G N S C L P D K L P I
Dog Lupus familis XP_850183 156 17406
Cat Felis silvestris
Mouse Mus musculus Q9JJR7 174 20227 S8 M D T R S Y P S P P D R L S V
Rat Rattus norvegicus Q64305 326 35287 P78 Q P A P S A A P H A L A P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508374 180 20345 N8 M D S K C F S N L P E M L P V
Chicken Gallus gallus P24899 311 33749 A66 P S P G P P A A A V P V I E L
Frog Xenopus laevis Q4ZHW1 270 30503 Y18 L E S F P S P Y F D E D D F F
Zebra Danio Brachydanio rerio Q7ZSX3 265 30428 Y18 L D S F S S S Y F D D D D F F
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 V97 A L D L K R E V P V I E L S R
Fruit Fly Dros. melanogaster Q9VGJ5 195 22106 L21 P D V P F Q P L W G Q E A P P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10007 268 30806 I44 P N P I Q H H I Q N H I Q T S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 93.9 38.8 N.A. 66.6 23.6 N.A. 63.3 23.7 24 23.7 21.8 23 N.A. 24.2 N.A.
Protein Similarity: 100 97.7 94.4 51.6 N.A. 79.4 32.2 N.A. 77.2 34 34.8 36.2 32 36.9 N.A. 40.6 N.A.
P-Site Identity: 100 100 93.3 0 N.A. 46.6 6.6 N.A. 46.6 0 0 20 6.6 13.3 N.A. 0 N.A.
P-Site Similarity: 100 100 93.3 0 N.A. 60 13.3 N.A. 80 26.6 33.3 40 20 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 16 8 8 8 0 8 8 0 0 % A
% Cys: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 54 8 0 0 0 0 0 0 16 39 16 16 0 0 % D
% Glu: 0 8 0 0 0 0 8 0 0 0 16 16 0 8 0 % E
% Phe: 0 0 0 16 8 8 0 0 16 0 0 0 0 16 16 % F
% Gly: 0 0 0 8 24 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 8 0 8 0 8 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 8 8 8 0 24 % I
% Lys: 0 0 0 8 8 0 0 0 0 0 0 24 0 0 0 % K
% Leu: 16 8 0 8 0 0 0 8 31 0 8 0 47 0 8 % L
% Met: 39 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 24 0 0 24 0 8 0 8 0 0 0 0 0 % N
% Pro: 24 8 16 16 16 8 24 8 16 39 8 0 8 47 16 % P
% Gln: 8 0 0 0 8 8 0 0 8 0 8 0 8 0 0 % Q
% Arg: 0 0 0 31 0 8 0 0 0 0 0 8 0 0 8 % R
% Ser: 0 8 24 0 24 16 39 24 0 0 0 0 0 16 8 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 8 0 0 0 0 8 0 16 0 8 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 16 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _