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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCL3
All Species:
13.64
Human Site:
T168
Identified Species:
25
UniProt:
Q9NQ33
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ33
NP_065697.1
180
20797
T168
K
V
S
S
M
I
A
T
T
S
H
H
A
D
P
Chimpanzee
Pan troglodytes
XP_522303
181
20906
T169
K
V
S
S
M
I
A
T
T
S
H
H
A
D
P
Rhesus Macaque
Macaca mulatta
XP_001102401
181
20820
T169
K
G
S
S
M
I
A
T
T
S
H
H
A
D
P
Dog
Lupus familis
XP_850183
156
17406
L147
L
S
A
A
H
I
S
L
S
F
V
V
I
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJR7
174
20227
G165
N
P
R
T
A
S
C
G
S
L
D
P
A
L
R
Rat
Rattus norvegicus
Q64305
326
35287
S238
G
C
G
G
P
G
G
S
R
H
L
G
G
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508374
180
20345
T168
K
V
Q
A
T
V
A
T
L
N
H
Q
T
D
P
Chicken
Gallus gallus
P24899
311
33749
V255
V
N
K
D
S
G
I
V
Q
E
D
L
L
Q
D
Frog
Xenopus laevis
Q4ZHW1
270
30503
V195
S
G
N
Q
P
K
K
V
I
I
C
H
R
G
T
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
V191
A
L
N
Q
P
K
K
V
I
I
C
H
R
G
T
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
M280
T
D
G
E
T
G
L
M
V
G
A
H
E
V
G
Fruit Fly
Dros. melanogaster
Q9VGJ5
195
22106
Y182
H
L
H
P
A
A
A
Y
Q
R
D
F
A
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10007
268
30806
E249
N
G
F
Q
E
E
S
E
G
N
I
L
I
D
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
93.9
38.8
N.A.
66.6
23.6
N.A.
63.3
23.7
24
23.7
21.8
23
N.A.
24.2
N.A.
Protein Similarity:
100
97.7
94.4
51.6
N.A.
79.4
32.2
N.A.
77.2
34
34.8
36.2
32
36.9
N.A.
40.6
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
6.6
N.A.
46.6
0
6.6
6.6
6.6
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
20
13.3
N.A.
66.6
0
13.3
20
6.6
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
16
16
8
39
0
0
0
8
0
39
0
0
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
16
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
24
0
0
47
8
% D
% Glu:
0
0
0
8
8
8
0
8
0
8
0
0
8
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
8
24
16
8
0
24
8
8
8
8
0
8
8
16
8
% G
% His:
8
0
8
0
8
0
0
0
0
8
31
47
0
0
0
% H
% Ile:
0
0
0
0
0
31
8
0
16
16
8
0
16
0
8
% I
% Lys:
31
0
8
0
0
16
16
0
0
0
0
0
0
0
0
% K
% Leu:
8
16
0
0
0
0
8
8
8
8
8
16
8
8
0
% L
% Met:
0
0
0
0
24
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
16
8
16
0
0
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
0
8
0
8
24
0
0
0
0
0
0
8
0
0
39
% P
% Gln:
0
0
8
24
0
0
0
0
16
0
0
8
0
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
8
8
0
0
16
0
8
% R
% Ser:
8
8
24
24
8
8
16
8
16
24
0
0
0
16
8
% S
% Thr:
8
0
0
8
16
0
0
31
24
0
0
0
8
0
16
% T
% Val:
8
24
0
0
0
8
0
24
8
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _