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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAN All Species: 36.06
Human Site: S198 Identified Species: 56.67
UniProt: Q9NQ55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ55 NP_001035754.1 473 53194 S198 E L D F R H Y S I K V V P V G
Chimpanzee Pan troglodytes XP_001150990 706 78742 S198 E L D F R H Y S I K V V P V G
Rhesus Macaque Macaca mulatta XP_001100297 471 52923 S198 E L D F R H Y S I K V V P V G
Dog Lupus familis XP_533920 792 88144 S198 E L D F R H Y S I K V V P V G
Cat Felis silvestris
Mouse Mus musculus Q91YU8 470 52707 S198 E L D F R H Y S V K V V P V G
Rat Rattus norvegicus NP_001011980 470 52521 S198 E L D F R H Y S I K V V P V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519003 490 55177 S198 L L D F R H Y S L K V V P V G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958871 522 59529 S197 E V E F R H Y S L K V V P V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDE5 460 53074 S197 L V E M R H Y S V Q V V P V G
Honey Bee Apis mellifera XP_395421 413 48031 M191 Q L K L I A S M F Q N M F P T
Nematode Worm Caenorhab. elegans NP_491108 573 63766 A226 E I Q M R H F A I R V V A S G
Sea Urchin Strong. purpuratus XP_787585 300 34175 S81 V A G P L G V S H F L S Y T K
Poplar Tree Populus trichocarpa XP_002302711 297 33281 H78 A G P M G V S H F L I L S K T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASU7 345 38823 I126 Q Y S L A S D I A Q S Q L R P
Baker's Yeast Sacchar. cerevisiae P38789 453 51746 F207 E I S M R H Y F I D I R E V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.1 95.7 48.8 N.A. 73.3 73.5 N.A. 62 N.A. N.A. 53 N.A. 35 38.9 31.4 36.3
Protein Similarity: 100 65.4 97.4 54 N.A. 81.6 81.8 N.A. 75.3 N.A. N.A. 70.1 N.A. 57.5 59.2 49.5 47.9
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 86.6 N.A. N.A. 80 N.A. 60 6.6 46.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 100 N.A. 86.6 26.6 73.3 13.3
Percent
Protein Identity: 28.7 N.A. N.A. 32.9 25.5 N.A.
Protein Similarity: 42.9 N.A. N.A. 50.5 44.8 N.A.
P-Site Identity: 0 N.A. N.A. 0 40 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 7 7 0 7 7 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 47 0 0 0 7 0 0 7 0 0 0 0 0 % D
% Glu: 60 0 14 0 0 0 0 0 0 0 0 0 7 0 7 % E
% Phe: 0 0 0 54 0 0 7 7 14 7 0 0 7 0 0 % F
% Gly: 0 7 7 0 7 7 0 0 0 0 0 0 0 0 67 % G
% His: 0 0 0 0 0 74 0 7 7 0 0 0 0 0 0 % H
% Ile: 0 14 0 0 7 0 0 7 47 0 14 0 0 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 54 0 0 0 7 7 % K
% Leu: 14 54 0 14 7 0 0 0 14 7 7 7 7 0 0 % L
% Met: 0 0 0 27 0 0 0 7 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 7 7 0 0 0 0 0 0 0 0 60 7 7 % P
% Gln: 14 0 7 0 0 0 0 0 0 20 0 7 0 0 0 % Q
% Arg: 0 0 0 0 74 0 0 0 0 7 0 7 0 7 0 % R
% Ser: 0 0 14 0 0 7 14 67 0 0 7 7 7 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 14 % T
% Val: 7 14 0 0 0 7 7 0 14 0 67 67 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 67 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _