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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAN All Species: 12.12
Human Site: S372 Identified Species: 19.05
UniProt: Q9NQ55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ55 NP_001035754.1 473 53194 S372 G I P S R T A S L E L G E D D
Chimpanzee Pan troglodytes XP_001150990 706 78742 S372 G I P S R T A S L E L G E D D
Rhesus Macaque Macaca mulatta XP_001100297 471 52923 S372 G I P S R T A S L G L G E E D
Dog Lupus familis XP_533920 792 88144 E372 E D P G A P P E T E G A G Q Q
Cat Felis silvestris
Mouse Mus musculus Q91YU8 470 52707 E372 E D P G A P P E A V G A G Q P
Rat Rattus norvegicus NP_001011980 470 52521 E372 E D P G A P P E A V G M S Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519003 490 55177 G372 E D P G P P T G G Q Q E A T Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958871 522 59529 Q371 E V E D P G M Q E G Q A P A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDE5 460 53074 T353 K R A A E G R T D S D P E D D
Honey Bee Apis mellifera XP_395421 413 48031 V331 E V L Y H E Y V F K S E E E K
Nematode Worm Caenorhab. elegans NP_491108 573 63766 E383 Q Q D A E E A E V K A I R E N
Sea Urchin Strong. purpuratus XP_787585 300 34175 R221 S K V P N L G R Y Q D V S D F
Poplar Tree Populus trichocarpa XP_002302711 297 33281 N218 R Q V P D L R N L Q D V S D F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASU7 345 38823 K266 S D L G R V N K G A T K S A V
Baker's Yeast Sacchar. cerevisiae P38789 453 51746 S361 H E F V Q K S S E E I K A L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.1 95.7 48.8 N.A. 73.3 73.5 N.A. 62 N.A. N.A. 53 N.A. 35 38.9 31.4 36.3
Protein Similarity: 100 65.4 97.4 54 N.A. 81.6 81.8 N.A. 75.3 N.A. N.A. 70.1 N.A. 57.5 59.2 49.5 47.9
P-Site Identity: 100 100 86.6 13.3 N.A. 6.6 6.6 N.A. 6.6 N.A. N.A. 0 N.A. 20 6.6 6.6 6.6
P-Site Similarity: 100 100 93.3 13.3 N.A. 6.6 6.6 N.A. 13.3 N.A. N.A. 13.3 N.A. 33.3 26.6 40 13.3
Percent
Protein Identity: 28.7 N.A. N.A. 32.9 25.5 N.A.
Protein Similarity: 42.9 N.A. N.A. 50.5 44.8 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 14 20 0 27 0 14 7 7 20 14 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 7 7 7 0 0 0 7 0 20 0 0 34 27 % D
% Glu: 40 7 7 0 14 14 0 27 14 27 0 14 34 20 14 % E
% Phe: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 14 % F
% Gly: 20 0 0 34 0 14 7 7 14 14 20 20 14 0 0 % G
% His: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 0 0 0 0 0 0 0 0 7 7 0 0 0 % I
% Lys: 7 7 0 0 0 7 0 7 0 14 0 14 0 0 7 % K
% Leu: 0 0 14 0 0 14 0 0 27 0 20 0 0 7 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 7 0 7 7 0 0 0 0 0 0 7 % N
% Pro: 0 0 47 14 14 27 20 0 0 0 0 7 7 0 7 % P
% Gln: 7 14 0 0 7 0 0 7 0 20 14 0 0 20 14 % Q
% Arg: 7 7 0 0 27 0 14 7 0 0 0 0 7 0 0 % R
% Ser: 14 0 0 20 0 0 7 27 0 7 7 0 27 0 0 % S
% Thr: 0 0 0 0 0 20 7 7 7 0 7 0 0 7 0 % T
% Val: 0 14 14 7 0 7 0 7 7 14 0 14 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 7 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _