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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
12.73
Human Site:
S399
Identified Species:
20
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
S399
Q
A
V
G
E
A
P
S
E
D
L
F
P
E
A
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
S399
Q
A
V
G
E
A
P
S
E
D
L
F
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
S399
Q
A
V
G
E
A
P
S
E
D
L
F
P
E
A
Dog
Lupus familis
XP_533920
792
88144
D398
Q
A
V
G
E
E
P
D
E
D
M
F
P
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
D398
Q
A
V
G
E
E
P
D
E
D
L
F
P
T
A
Rat
Rattus norvegicus
NP_001011980
470
52521
D398
Q
A
V
G
E
E
P
D
E
D
L
F
P
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
D399
Q
A
V
G
E
E
P
D
E
D
L
F
P
G
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
D396
Q
A
V
G
E
E
P
D
E
D
M
F
P
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
S389
K
S
S
R
K
R
P
S
L
G
G
G
M
K
Y
Honey Bee
Apis mellifera
XP_395421
413
48031
K356
K
K
L
K
E
K
R
K
K
I
Q
E
E
N
K
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
E420
R
E
I
A
M
N
R
E
R
D
L
K
R
A
N
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
H246
E
A
E
L
D
G
E
H
N
E
V
T
L
P
Q
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
T243
E
G
D
D
E
A
A
T
V
T
L
A
N
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
E291
M
Q
L
V
K
V
E
E
G
L
C
T
G
G
I
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
E386
E
Q
R
K
K
E
Q
E
E
N
I
A
K
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
73.3
N.A.
80
73.3
N.A.
80
N.A.
N.A.
73.3
N.A.
13.3
6.6
13.3
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
73.3
N.A.
80
N.A.
N.A.
80
N.A.
40
26.6
26.6
33.3
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
20
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
7
0
27
7
0
0
0
0
14
0
7
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
7
7
7
0
0
34
0
60
0
0
0
7
0
% D
% Glu:
20
7
7
0
67
40
14
20
60
7
0
7
7
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% F
% Gly:
0
7
0
54
0
7
0
0
7
7
7
7
7
20
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
7
7
0
0
0
7
% I
% Lys:
14
7
0
14
20
7
0
7
7
0
0
7
7
20
14
% K
% Leu:
0
0
14
7
0
0
0
0
7
7
54
0
7
0
7
% L
% Met:
7
0
0
0
7
0
0
0
0
0
14
0
7
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
7
7
0
0
7
7
7
% N
% Pro:
0
0
0
0
0
0
60
0
0
0
0
0
54
7
0
% P
% Gln:
54
14
0
0
0
0
7
0
0
0
7
0
0
0
7
% Q
% Arg:
7
0
7
7
0
7
14
0
7
0
0
0
7
0
0
% R
% Ser:
0
7
7
0
0
0
0
27
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
7
0
14
0
14
0
% T
% Val:
0
0
54
7
0
7
0
0
7
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _