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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
40.61
Human Site:
T280
Identified Species:
63.81
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
T280
T
E
I
G
P
R
M
T
L
Q
L
I
K
V
Q
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
T280
T
E
I
G
P
R
M
T
L
Q
L
I
K
V
Q
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
T280
T
E
I
G
P
R
M
T
L
Q
L
I
K
V
Q
Dog
Lupus familis
XP_533920
792
88144
T280
T
E
I
G
P
R
M
T
L
Q
L
I
K
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
T280
T
E
I
G
P
R
M
T
L
Q
L
I
K
I
Q
Rat
Rattus norvegicus
NP_001011980
470
52521
T280
T
E
I
G
P
R
M
T
L
Q
L
I
K
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
T280
T
E
I
G
P
R
M
T
L
Q
L
T
K
I
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
T279
T
E
I
G
P
R
M
T
L
Q
L
V
K
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
T278
H
E
I
G
P
R
L
T
M
Q
L
I
K
I
E
Honey Bee
Apis mellifera
XP_395421
413
48031
S271
T
K
E
T
V
S
E
S
E
V
E
D
D
P
L
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
T313
H
E
I
G
P
R
L
T
L
E
L
V
K
I
E
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
M161
M
T
T
M
F
Q
N
M
F
P
S
I
N
V
N
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
F158
T
V
M
F
Q
K
I
F
P
A
I
D
I
N
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
L206
F
R
H
Y
S
I
R
L
Q
P
V
G
V
S
R
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
K291
S
Q
R
T
P
V
E
K
K
D
N
K
E
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
80
N.A.
66.6
6.6
60
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
93.3
N.A.
93.3
20
93.3
20
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
14
7
0
0
% D
% Glu:
0
67
7
0
0
0
14
0
7
7
7
0
7
0
20
% E
% Phe:
7
0
0
7
7
0
0
7
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
67
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
14
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
67
0
0
7
7
0
0
0
7
54
7
47
0
% I
% Lys:
0
7
0
0
0
7
0
7
7
0
0
7
67
0
0
% K
% Leu:
0
0
0
0
0
0
14
7
60
0
67
0
0
0
7
% L
% Met:
7
0
7
7
0
0
54
7
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
0
7
7
7
% N
% Pro:
0
0
0
0
74
0
0
0
7
14
0
0
0
7
0
% P
% Gln:
0
7
0
0
7
7
0
0
7
60
0
0
0
0
47
% Q
% Arg:
0
7
7
0
0
67
7
0
0
0
0
0
0
7
7
% R
% Ser:
7
0
0
0
7
7
0
7
0
0
7
0
0
7
0
% S
% Thr:
67
7
7
14
0
0
0
67
0
0
0
7
0
0
7
% T
% Val:
0
7
0
0
7
7
0
0
0
7
7
14
7
27
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _