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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAN All Species: 19.7
Human Site: T35 Identified Species: 30.95
UniProt: Q9NQ55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ55 NP_001035754.1 473 53194 T35 N P H S F V F T R G C T G R N
Chimpanzee Pan troglodytes XP_001150990 706 78742 T35 N P H S F V F T R G C T G R N
Rhesus Macaque Macaca mulatta XP_001100297 471 52923 T35 N P H S F V F T R G C T G R N
Dog Lupus familis XP_533920 792 88144 A35 Q P H S F V F A R G R A G R G
Cat Felis silvestris
Mouse Mus musculus Q91YU8 470 52707 T35 Q P H S F V F T R G R A G R N
Rat Rattus norvegicus NP_001011980 470 52521 T35 Q P H S F V F T R G R A G R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519003 490 55177 S35 A P H S F V F S R G A V G K T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958871 522 59529 H34 V P H T F V F H R G Q V G K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDE5 460 53074 H34 A P H S F V I H R G L A C P Y
Honey Bee Apis mellifera XP_395421 413 48031 W32 Q L L N Y A F W P Q H E I R Q
Nematode Worm Caenorhab. elegans NP_491108 573 63766 H62 Q P H C L V I H R G D V G K Y
Sea Urchin Strong. purpuratus XP_787585 300 34175
Poplar Tree Populus trichocarpa XP_002302711 297 33281
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASU7 345 38823
Baker's Yeast Sacchar. cerevisiae P38789 453 51746 Q32 S M V I R V G Q T S L A N H S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.1 95.7 48.8 N.A. 73.3 73.5 N.A. 62 N.A. N.A. 53 N.A. 35 38.9 31.4 36.3
Protein Similarity: 100 65.4 97.4 54 N.A. 81.6 81.8 N.A. 75.3 N.A. N.A. 70.1 N.A. 57.5 59.2 49.5 47.9
P-Site Identity: 100 100 100 66.6 N.A. 80 73.3 N.A. 60 N.A. N.A. 60 N.A. 46.6 13.3 40 0
P-Site Similarity: 100 100 100 66.6 N.A. 80 80 N.A. 73.3 N.A. N.A. 73.3 N.A. 46.6 26.6 46.6 0
Percent
Protein Identity: 28.7 N.A. N.A. 32.9 25.5 N.A.
Protein Similarity: 42.9 N.A. N.A. 50.5 44.8 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 0 N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 7 0 7 0 0 7 34 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 20 0 7 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 60 0 60 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 67 0 0 60 0 7 % G
% His: 0 0 67 0 0 0 0 20 0 0 7 0 0 7 0 % H
% Ile: 0 0 0 7 0 0 14 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 0 7 7 0 7 0 0 0 0 0 14 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 0 7 0 0 0 0 0 0 0 0 7 0 34 % N
% Pro: 0 67 0 0 0 0 0 0 7 0 0 0 0 7 0 % P
% Gln: 34 0 0 0 0 0 0 7 0 7 7 0 0 0 7 % Q
% Arg: 0 0 0 0 7 0 0 0 67 0 20 0 0 47 0 % R
% Ser: 7 0 0 54 0 0 0 7 0 7 0 0 0 0 14 % S
% Thr: 0 0 0 7 0 0 0 34 7 0 0 20 0 0 7 % T
% Val: 7 0 7 0 0 74 0 0 0 0 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _