Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAN All Species: 40.61
Human Site: T58 Identified Species: 63.81
UniProt: Q9NQ55 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ55 NP_001035754.1 473 53194 T58 R R V M E P L T A S R L Q V R
Chimpanzee Pan troglodytes XP_001150990 706 78742 T58 R R V M E P L T A S R L Q V R
Rhesus Macaque Macaca mulatta XP_001100297 471 52923 T58 R R V M E P L T A S R L Q V R
Dog Lupus familis XP_533920 792 88144 T58 R R V M E P L T A T R L Q I R
Cat Felis silvestris
Mouse Mus musculus Q91YU8 470 52707 T58 R R V M E P L T A T R L Q V R
Rat Rattus norvegicus NP_001011980 470 52521 T58 R R V L E P L T A T R L Q V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519003 490 55177 T58 R R V M E P Y T A S A L Q V R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958871 522 59529 T57 R R V M E P F T A R S L K V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDE5 460 53074 T57 R R I M E P F T A S N L R E K
Honey Bee Apis mellifera XP_395421 413 48031 P55 Q I N T E E N P D I V K A P H
Nematode Worm Caenorhab. elegans NP_491108 573 63766 T85 R N L V E P N T A K N L K I L
Sea Urchin Strong. purpuratus XP_787585 300 34175
Poplar Tree Populus trichocarpa XP_002302711 297 33281
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ASU7 345 38823
Baker's Yeast Sacchar. cerevisiae P38789 453 51746 T55 R Q I M Q P H T A I K L K E R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.1 95.7 48.8 N.A. 73.3 73.5 N.A. 62 N.A. N.A. 53 N.A. 35 38.9 31.4 36.3
Protein Similarity: 100 65.4 97.4 54 N.A. 81.6 81.8 N.A. 75.3 N.A. N.A. 70.1 N.A. 57.5 59.2 49.5 47.9
P-Site Identity: 100 100 100 86.6 N.A. 93.3 86.6 N.A. 86.6 N.A. N.A. 73.3 N.A. 60 6.6 40 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 N.A. N.A. 80 N.A. 80 13.3 66.6 0
Percent
Protein Identity: 28.7 N.A. N.A. 32.9 25.5 N.A.
Protein Similarity: 42.9 N.A. N.A. 50.5 44.8 N.A.
P-Site Identity: 0 N.A. N.A. 0 46.6 N.A.
P-Site Similarity: 0 N.A. N.A. 0 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 74 0 7 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 74 7 0 0 0 0 0 0 0 14 0 % E
% Phe: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % H
% Ile: 0 7 14 0 0 0 0 0 0 14 0 0 0 14 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 7 7 20 0 7 % K
% Leu: 0 0 7 7 0 0 40 0 0 0 0 74 0 0 7 % L
% Met: 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 14 0 0 0 14 0 0 0 0 % N
% Pro: 0 0 0 0 0 74 0 7 0 0 0 0 0 7 0 % P
% Gln: 7 7 0 0 7 0 0 0 0 0 0 0 47 0 0 % Q
% Arg: 74 60 0 0 0 0 0 0 0 7 40 0 7 0 60 % R
% Ser: 0 0 0 0 0 0 0 0 0 34 7 0 0 0 0 % S
% Thr: 0 0 0 7 0 0 0 74 0 20 0 0 0 0 0 % T
% Val: 0 0 54 7 0 0 0 0 0 0 7 0 0 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _