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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASS4
All Species:
5.45
Human Site:
S274
Identified Species:
12
UniProt:
Q9NQ75
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ75
NP_001157588.1
786
87144
S274
S
R
P
H
A
L
P
S
S
S
S
T
F
Y
N
Chimpanzee
Pan troglodytes
XP_001169779
786
87081
I274
S
R
P
H
A
L
P
I
C
S
S
T
F
H
N
Rhesus Macaque
Macaca mulatta
XP_001090515
786
86837
S274
S
R
P
H
A
L
P
S
S
G
S
T
F
H
N
Dog
Lupus familis
XP_534461
746
82524
D256
Y
K
F
L
A
P
R
D
T
I
P
L
D
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q08EC4
804
88602
P272
D
S
G
S
R
A
I
P
G
S
S
A
V
H
T
Rat
Rattus norvegicus
Q63767
968
104244
P397
S
V
E
K
G
L
P
P
S
N
H
H
S
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509857
821
90320
P304
D
V
P
P
A
R
N
P
P
G
S
H
H
S
P
Chicken
Gallus gallus
XP_417499
814
90427
P296
N
Q
V
L
Y
D
I
P
P
A
R
Y
K
A
L
Frog
Xenopus laevis
NP_001084484
853
95724
Y285
S
L
D
R
Q
M
V
Y
D
V
P
P
T
R
Y
Zebra Danio
Brachydanio rerio
XP_001341038
774
86396
P281
P
L
Y
D
V
P
K
P
S
I
S
L
T
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782316
831
91548
S271
D
T
Y
D
I
P
P
S
Q
Q
G
D
N
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.6
64.2
N.A.
61
22.3
N.A.
51.4
43.4
38.5
29
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
98.8
96
72.3
N.A.
71.5
38
N.A.
66.8
60.5
55.6
45.2
N.A.
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
80
86.6
6.6
N.A.
13.3
26.6
N.A.
20
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
86.6
93.3
26.6
N.A.
20
33.3
N.A.
20
20
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
46
10
0
0
0
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
28
0
10
19
0
10
0
10
10
0
0
10
10
10
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
28
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
10
19
10
0
0
0
0
% G
% His:
0
0
0
28
0
0
0
0
0
0
10
19
10
28
0
% H
% Ile:
0
0
0
0
10
0
19
10
0
19
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
10
0
0
0
0
0
10
0
0
% K
% Leu:
0
19
0
19
0
37
0
0
0
0
0
19
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
0
10
0
0
10
0
28
% N
% Pro:
10
0
37
10
0
28
46
46
19
0
19
10
0
0
10
% P
% Gln:
0
10
0
0
10
0
0
0
10
10
0
0
0
10
0
% Q
% Arg:
0
28
0
10
10
10
10
0
0
0
10
0
0
10
0
% R
% Ser:
46
10
0
10
0
0
0
28
37
28
55
0
10
10
19
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
0
28
19
0
10
% T
% Val:
0
19
10
0
10
0
10
0
0
10
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
19
0
10
0
0
10
0
0
0
10
0
10
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _