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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASS4 All Species: 15.76
Human Site: S429 Identified Species: 34.67
UniProt: Q9NQ75 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ75 NP_001157588.1 786 87144 S429 S S S S S E E S A K E L S L D
Chimpanzee Pan troglodytes XP_001169779 786 87081 S429 S S S S S E E S A K E L S L D
Rhesus Macaque Macaca mulatta XP_001090515 786 86837 S429 S S S S S E E S A K E L S L D
Dog Lupus familis XP_534461 746 82524 N411 F R D Y L E A N L G A I R T A
Cat Felis silvestris
Mouse Mus musculus Q08EC4 804 88602 S427 S G S S S E D S V K E L W M D
Rat Rattus norvegicus Q63767 968 104244 L552 V V P G R E P L E L E V A V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509857 821 90320 D459 S S L S S P E D Q E A A A L D
Chicken Gallus gallus XP_417499 814 90427 P451 S A S S S D E P D K E I K L D
Frog Xenopus laevis NP_001084484 853 95724 S440 T M S S L E V S I K Q E T L E
Zebra Danio Brachydanio rerio XP_001341038 774 86396 K436 A V C Q S V P K L M L F V S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782316 831 91548 L426 A D C I D E T L G R R L N L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 93.6 64.2 N.A. 61 22.3 N.A. 51.4 43.4 38.5 29 N.A. N.A. N.A. N.A. 23.8
Protein Similarity: 100 98.8 96 72.3 N.A. 71.5 38 N.A. 66.8 60.5 55.6 45.2 N.A. N.A. N.A. N.A. 39.7
P-Site Identity: 100 100 100 6.6 N.A. 66.6 13.3 N.A. 46.6 60 40 6.6 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 20 N.A. 80 40 N.A. 60 80 66.6 13.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 0 0 10 0 28 0 19 10 19 0 10 % A
% Cys: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 10 10 10 10 10 0 0 0 0 0 64 % D
% Glu: 0 0 0 0 0 73 46 0 10 10 55 10 0 0 19 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 10 0 10 0 0 0 0 10 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 19 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 55 0 0 10 0 0 % K
% Leu: 0 0 10 0 19 0 0 19 19 10 10 46 0 64 0 % L
% Met: 0 10 0 0 0 0 0 0 0 10 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 0 10 19 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 0 10 0 0 10 0 0 0 0 10 10 0 10 0 0 % R
% Ser: 55 37 55 64 64 0 0 46 0 0 0 0 28 10 10 % S
% Thr: 10 0 0 0 0 0 10 0 0 0 0 0 10 10 0 % T
% Val: 10 19 0 0 0 10 10 0 10 0 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _