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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPRC5C
All Species:
13.94
Human Site:
Y438
Identified Species:
38.33
UniProt:
Q9NQ84
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ84
NP_061123.3
441
48193
Y438
S
Q
V
F
R
N
P
Y
V
W
D
_
_
_
_
Chimpanzee
Pan troglodytes
XP_523705
867
92897
T853
N
S
Q
V
S
E
L
T
Q
R
G
Q
A
N
T
Rhesus Macaque
Macaca mulatta
XP_001089162
541
58664
Y538
S
Q
V
F
R
N
P
Y
V
W
D
_
_
_
_
Dog
Lupus familis
XP_540407
571
62064
Y568
S
Q
V
F
R
N
P
Y
V
W
D
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3J9
440
48403
Y437
S
Q
V
F
R
N
P
Y
V
W
D
_
_
_
_
Rat
Rattus norvegicus
Q3KRC4
441
48431
N437
S
Q
D
Q
S
P
K
N
K
T
R
W
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510838
653
70143
I624
Y
G
S
T
I
G
T
I
G
G
G
V
F
W
E
Chicken
Gallus gallus
XP_425386
441
47466
P425
Q
Q
E
P
V
V
K
P
R
S
Y
S
T
G
A
Frog
Xenopus laevis
NP_001093385
432
48227
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.3
78.7
71
N.A.
89.3
88.4
N.A.
49.4
58.5
61.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.8
80
73.5
N.A.
92.2
90.9
N.A.
54.8
67.1
72.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
16.6
N.A.
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
16.6
N.A.
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
45
0
0
0
0
% D
% Glu:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
45
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
0
0
12
0
0
12
12
23
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
23
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
45
0
12
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
12
0
12
45
12
0
0
0
0
0
0
0
% P
% Gln:
12
67
12
12
0
0
0
0
12
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
45
0
0
0
12
12
12
0
0
0
0
% R
% Ser:
56
12
12
0
23
0
0
0
0
12
0
12
0
0
0
% S
% Thr:
0
0
0
12
0
0
12
12
0
12
0
0
12
0
12
% T
% Val:
0
0
45
12
12
12
0
0
45
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
45
0
12
0
12
0
% W
% Tyr:
12
0
0
0
0
0
0
45
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
45
56
56
56
% _