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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEYL
All Species:
10.3
Human Site:
S139
Identified Species:
20.61
UniProt:
Q9NQ87
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ87
NP_055386.1
328
35087
S139
L
G
V
L
E
G
P
S
S
R
A
D
P
V
R
Chimpanzee
Pan troglodytes
XP_001171234
328
35074
S139
L
G
V
L
E
G
P
S
S
R
A
D
P
V
R
Rhesus Macaque
Macaca mulatta
XP_001113370
328
35206
S139
L
G
V
L
E
G
P
S
S
R
A
D
P
V
R
Dog
Lupus familis
XP_849702
326
34903
G137
R
Y
L
G
V
L
E
G
P
S
S
R
A
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBX7
326
34910
G137
R
Y
L
G
V
L
E
G
P
S
S
H
A
D
P
Rat
Rattus norvegicus
Q04666
281
29603
R93
K
H
L
R
N
L
Q
R
A
Q
M
T
A
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515594
298
32215
A110
T
G
F
F
D
A
R
A
L
A
V
D
Y
R
S
Chicken
Gallus gallus
O57337
290
31053
S102
A
Q
M
A
A
A
L
S
A
D
P
S
V
L
G
Frog
Xenopus laevis
Q9I8A3
294
32117
G106
L
H
T
A
G
G
K
G
Y
F
D
A
H
A
L
Zebra Danio
Brachydanio rerio
Q8AXV5
310
33373
R122
D
Y
R
T
L
G
F
R
E
C
V
G
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
M196
Y
L
V
T
I
E
G
M
D
I
Q
D
P
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
D129
V
E
G
M
D
I
Q
D
P
L
R
L
R
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
87.5
N.A.
77.7
28.6
N.A.
56
28.6
46.3
45.7
N.A.
28.2
N.A.
N.A.
37.5
Protein Similarity:
100
99
95.7
91.1
N.A.
82.9
41.1
N.A.
66.1
42.3
59.4
56
N.A.
43
N.A.
N.A.
52.1
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
13.3
6.6
13.3
13.3
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
20
N.A.
26.6
26.6
13.3
13.3
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
9
17
0
9
17
9
25
9
25
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
0
17
0
0
9
9
9
9
42
0
17
0
% D
% Glu:
0
9
0
0
25
9
17
0
9
0
0
0
9
0
0
% E
% Phe:
0
0
9
9
0
0
9
0
0
9
0
0
0
0
0
% F
% Gly:
0
34
9
17
9
42
9
25
0
0
0
9
0
0
9
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
34
9
25
25
9
25
9
0
9
9
0
9
0
25
17
% L
% Met:
0
0
9
9
0
0
0
9
0
0
9
0
0
0
9
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
25
0
25
0
9
0
34
0
17
% P
% Gln:
0
9
0
0
0
0
17
0
0
9
9
0
0
0
0
% Q
% Arg:
17
0
9
9
0
0
9
17
0
25
9
9
9
9
34
% R
% Ser:
0
0
0
0
0
0
0
34
25
17
17
9
0
0
9
% S
% Thr:
9
0
9
17
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
9
0
34
0
17
0
0
0
0
0
17
0
9
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
25
0
0
0
0
0
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _