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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEYL
All Species:
11.52
Human Site:
S239
Identified Species:
23.03
UniProt:
Q9NQ87
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ87
NP_055386.1
328
35087
S239
A
R
R
N
V
L
P
S
R
G
A
S
S
T
R
Chimpanzee
Pan troglodytes
XP_001171234
328
35074
S239
A
R
R
N
V
L
P
S
R
G
A
S
S
T
R
Rhesus Macaque
Macaca mulatta
XP_001113370
328
35206
S239
A
R
R
N
V
L
P
S
R
G
A
S
S
T
R
Dog
Lupus familis
XP_849702
326
34903
L237
L
P
A
R
R
N
L
L
P
S
R
G
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBX7
326
34910
L237
P
P
T
R
R
N
L
L
P
S
R
G
V
T
S
Rat
Rattus norvegicus
Q04666
281
29603
G193
P
P
L
V
P
I
P
G
G
A
A
P
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515594
298
32215
L210
A
L
L
T
A
S
S
L
A
Y
P
G
P
T
P
Chicken
Gallus gallus
O57337
290
31053
G202
A
L
S
P
K
V
Y
G
G
F
Q
L
V
P
A
Frog
Xenopus laevis
Q9I8A3
294
32117
A206
S
T
S
S
S
T
E
A
H
H
H
N
R
L
R
Zebra Danio
Brachydanio rerio
Q8AXV5
310
33373
S222
S
P
A
L
R
M
G
S
L
S
T
Q
G
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
S296
S
G
S
A
V
T
E
S
L
P
S
H
D
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
Q229
S
H
A
E
T
Q
L
Q
T
S
C
H
G
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
87.5
N.A.
77.7
28.6
N.A.
56
28.6
46.3
45.7
N.A.
28.2
N.A.
N.A.
37.5
Protein Similarity:
100
99
95.7
91.1
N.A.
82.9
41.1
N.A.
66.1
42.3
59.4
56
N.A.
43
N.A.
N.A.
52.1
P-Site Identity:
100
100
100
0
N.A.
6.6
13.3
N.A.
13.3
6.6
6.6
13.3
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
20
N.A.
13.3
13.3
33.3
26.6
N.A.
26.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
25
9
9
0
0
9
9
9
34
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
9
17
17
25
0
25
17
0
9
% G
% His:
0
9
0
0
0
0
0
0
9
9
9
17
0
0
9
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
17
17
9
0
25
25
25
17
0
0
9
0
17
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
0
17
0
0
0
0
0
9
0
0
0
% N
% Pro:
17
34
0
9
9
0
34
0
17
9
9
9
17
17
9
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
9
9
0
0
0
% Q
% Arg:
0
25
25
17
25
0
0
0
25
0
17
0
9
9
34
% R
% Ser:
34
0
25
9
9
9
9
42
0
34
9
25
25
9
17
% S
% Thr:
0
9
9
9
9
17
0
0
9
0
9
0
0
50
0
% T
% Val:
0
0
0
9
34
9
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _