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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEYL All Species: 3.94
Human Site: S38 Identified Species: 7.88
UniProt: Q9NQ87 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ87 NP_055386.1 328 35087 S38 R P L S T P S S S Q M Q A R K
Chimpanzee Pan troglodytes XP_001171234 328 35074 P38 R P L S T P S P S Q M Q A R K
Rhesus Macaque Macaca mulatta XP_001113370 328 35206 P38 R P L S T P S P S Q M Q A R K
Dog Lupus familis XP_849702 326 34903 P38 R P L S T P S P S Q M Q A R K
Cat Felis silvestris
Mouse Mus musculus Q9DBX7 326 34910 P38 R P L T T P S P S Q M Q A R K
Rat Rattus norvegicus Q04666 281 29603
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515594 298 32215 G16 S S D T E S D G I I D V G K E
Chicken Gallus gallus O57337 290 31053 E8 M P A D T G M E K P T A S P I
Frog Xenopus laevis Q9I8A3 294 32117 S12 H D Y S S S D S E L D E N I E
Zebra Danio Brachydanio rerio Q8AXV5 310 33373 P28 G Q E D S Y C P V T G S M S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KM13 425 46797 S95 I S P S E P G S C Q L M S R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783676 317 34739 E35 K K R R G I I E K R R R D R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.2 87.5 N.A. 77.7 28.6 N.A. 56 28.6 46.3 45.7 N.A. 28.2 N.A. N.A. 37.5
Protein Similarity: 100 99 95.7 91.1 N.A. 82.9 41.1 N.A. 66.1 42.3 59.4 56 N.A. 43 N.A. N.A. 52.1
P-Site Identity: 100 93.3 93.3 93.3 N.A. 86.6 0 N.A. 0 13.3 13.3 0 N.A. 40 N.A. N.A. 6.6
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 0 N.A. 20 20 33.3 6.6 N.A. 53.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 9 42 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % C
% Asp: 0 9 9 17 0 0 17 0 0 0 17 0 9 0 0 % D
% Glu: 0 0 9 0 17 0 0 17 9 0 0 9 0 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 9 9 9 9 0 0 9 0 9 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 9 9 0 9 9 0 0 0 9 17 % I
% Lys: 9 9 0 0 0 0 0 0 17 0 0 0 0 9 50 % K
% Leu: 0 0 42 0 0 0 0 0 0 9 9 0 0 0 0 % L
% Met: 9 0 0 0 0 0 9 0 0 0 42 9 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 50 9 0 0 50 0 42 0 9 0 0 0 9 9 % P
% Gln: 0 9 0 0 0 0 0 0 0 50 0 42 0 0 0 % Q
% Arg: 42 0 9 9 0 0 0 0 0 9 9 9 0 59 0 % R
% Ser: 9 17 0 50 17 17 42 25 42 0 0 9 17 9 0 % S
% Thr: 0 0 0 17 50 0 0 0 0 9 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _