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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEYL
All Species:
16.67
Human Site:
S62
Identified Species:
33.33
UniProt:
Q9NQ87
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ87
NP_055386.1
328
35087
S62
R
R
D
R
I
N
S
S
L
S
E
L
R
R
L
Chimpanzee
Pan troglodytes
XP_001171234
328
35074
S62
R
R
D
R
I
N
S
S
L
S
E
L
R
R
L
Rhesus Macaque
Macaca mulatta
XP_001113370
328
35206
S62
R
R
D
R
I
N
S
S
L
S
E
L
R
R
L
Dog
Lupus familis
XP_849702
326
34903
N60
K
R
R
R
D
R
I
N
S
S
L
S
E
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBX7
326
34910
N60
K
R
R
R
D
R
I
N
S
S
L
S
E
L
R
Rat
Rattus norvegicus
Q04666
281
29603
A16
N
S
S
S
P
V
A
A
T
P
A
S
V
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515594
298
32215
S33
S
Q
I
S
R
S
V
S
P
T
T
T
S
Q
M
Chicken
Gallus gallus
O57337
290
31053
T25
A
P
A
S
A
S
H
T
P
D
K
P
R
S
A
Frog
Xenopus laevis
Q9I8A3
294
32117
G29
K
E
S
A
D
E
N
G
N
L
S
S
M
S
P
Zebra Danio
Brachydanio rerio
Q8AXV5
310
33373
K45
T
S
Q
I
L
A
R
K
K
R
R
G
I
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
S119
R
R
D
R
I
N
S
S
L
T
E
L
K
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
L52
S
L
T
E
L
R
R
L
V
P
A
A
F
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
87.5
N.A.
77.7
28.6
N.A.
56
28.6
46.3
45.7
N.A.
28.2
N.A.
N.A.
37.5
Protein Similarity:
100
99
95.7
91.1
N.A.
82.9
41.1
N.A.
66.1
42.3
59.4
56
N.A.
43
N.A.
N.A.
52.1
P-Site Identity:
100
100
100
20
N.A.
20
0
N.A.
6.6
6.6
0
0
N.A.
86.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
13.3
N.A.
40
26.6
13.3
6.6
N.A.
100
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
9
9
9
9
0
0
17
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
25
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
9
0
9
0
9
0
0
0
0
34
0
17
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
34
0
17
0
0
0
0
0
9
9
0
% I
% Lys:
25
0
0
0
0
0
0
9
9
0
9
0
9
0
9
% K
% Leu:
0
9
0
0
17
0
0
9
34
9
17
34
0
17
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
9
0
0
0
0
34
9
17
9
0
0
0
0
9
0
% N
% Pro:
0
9
0
0
9
0
0
0
17
17
0
9
0
0
9
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
34
50
17
50
9
25
17
0
0
9
9
0
34
34
17
% R
% Ser:
17
17
17
25
0
17
34
42
17
42
9
34
9
17
0
% S
% Thr:
9
0
9
0
0
0
0
9
9
17
9
9
0
0
9
% T
% Val:
0
0
0
0
0
9
9
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _