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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEYL All Species: 13.94
Human Site: S8 Identified Species: 27.88
UniProt: Q9NQ87 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ87 NP_055386.1 328 35087 S8 M K R P K E P S G S D G E S D
Chimpanzee Pan troglodytes XP_001171234 328 35074 S8 M K R P K E P S G S D G E S D
Rhesus Macaque Macaca mulatta XP_001113370 328 35206 R8 M K R P K E P R G S D G E S D
Dog Lupus familis XP_849702 326 34903 S8 M K R P R E P S G S D S E S D
Cat Felis silvestris
Mouse Mus musculus Q9DBX7 326 34910 S8 M K R P R A P S G S D G E S D
Rat Rattus norvegicus Q04666 281 29603
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515594 298 32215
Chicken Gallus gallus O57337 290 31053
Frog Xenopus laevis Q9I8A3 294 32117
Zebra Danio Brachydanio rerio Q8AXV5 310 33373
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KM13 425 46797 S65 G H S H G I G S L K R T L S E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783676 317 34739
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.2 87.5 N.A. 77.7 28.6 N.A. 56 28.6 46.3 45.7 N.A. 28.2 N.A. N.A. 37.5
Protein Similarity: 100 99 95.7 91.1 N.A. 82.9 41.1 N.A. 66.1 42.3 59.4 56 N.A. 43 N.A. N.A. 52.1
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 0 N.A. 0 0 0 0 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 0 N.A. 0 0 0 0 N.A. 20 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 42 0 0 0 42 % D
% Glu: 0 0 0 0 0 34 0 0 0 0 0 0 42 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 9 0 9 0 42 0 0 34 0 0 0 % G
% His: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 42 0 0 25 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % L
% Met: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 42 0 0 42 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 42 0 17 0 0 9 0 0 9 0 0 0 0 % R
% Ser: 0 0 9 0 0 0 0 42 0 42 0 9 0 50 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _