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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEYL
All Species:
12.73
Human Site:
T245
Identified Species:
25.45
UniProt:
Q9NQ87
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ87
NP_055386.1
328
35087
T245
P
S
R
G
A
S
S
T
R
R
A
R
P
L
E
Chimpanzee
Pan troglodytes
XP_001171234
328
35074
T245
P
S
R
G
A
S
S
T
R
R
A
R
P
L
E
Rhesus Macaque
Macaca mulatta
XP_001113370
328
35206
T245
P
S
R
G
A
S
S
T
R
R
G
R
P
L
E
Dog
Lupus familis
XP_849702
326
34903
S243
L
L
P
S
R
G
A
S
S
T
R
R
A
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBX7
326
34910
T243
L
L
P
S
R
G
V
T
S
T
Q
R
A
H
L
Rat
Rattus norvegicus
Q04666
281
29603
P199
P
G
G
A
A
P
P
P
G
S
A
P
C
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515594
298
32215
T216
S
L
A
Y
P
G
P
T
P
R
S
A
P
L
R
Chicken
Gallus gallus
O57337
290
31053
P208
Y
G
G
F
Q
L
V
P
A
T
D
G
Q
F
A
Frog
Xenopus laevis
Q9I8A3
294
32117
L212
E
A
H
H
H
N
R
L
R
G
S
P
H
A
E
Zebra Danio
Brachydanio rerio
Q8AXV5
310
33373
T228
G
S
L
S
T
Q
G
T
I
L
N
P
A
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
L302
E
S
L
P
S
H
D
L
H
S
D
S
S
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783676
317
34739
R235
L
Q
T
S
C
H
G
R
L
P
M
P
V
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
87.5
N.A.
77.7
28.6
N.A.
56
28.6
46.3
45.7
N.A.
28.2
N.A.
N.A.
37.5
Protein Similarity:
100
99
95.7
91.1
N.A.
82.9
41.1
N.A.
66.1
42.3
59.4
56
N.A.
43
N.A.
N.A.
52.1
P-Site Identity:
100
100
93.3
6.6
N.A.
13.3
20
N.A.
26.6
0
13.3
20
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
20
N.A.
13.3
20
N.A.
33.3
0
33.3
20
N.A.
20
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
34
0
9
0
9
0
25
9
25
9
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
17
0
0
0
0
% D
% Glu:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
17
17
25
0
25
17
0
9
9
9
9
0
0
0
% G
% His:
0
0
9
9
9
17
0
0
9
0
0
0
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
25
25
17
0
0
9
0
17
9
9
0
0
0
42
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
34
0
17
9
9
9
17
17
9
9
0
34
34
9
17
% P
% Gln:
0
9
0
0
9
9
0
0
0
0
9
0
9
0
9
% Q
% Arg:
0
0
25
0
17
0
9
9
34
34
9
42
0
9
9
% R
% Ser:
9
42
0
34
9
25
25
9
17
17
17
9
9
9
0
% S
% Thr:
0
0
9
0
9
0
0
50
0
25
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
17
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _