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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIGAR
All Species:
13.64
Human Site:
S184
Identified Species:
30
UniProt:
Q9NQ88
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ88
NP_065108.1
270
30063
S184
S
S
K
V
N
S
D
S
G
I
P
G
L
A
A
Chimpanzee
Pan troglodytes
XP_522324
270
30026
S184
S
S
K
V
N
S
D
S
G
I
P
G
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001118082
270
29997
S184
S
S
E
V
N
S
D
S
G
V
P
G
L
A
A
Dog
Lupus familis
XP_543863
316
34501
S230
A
P
E
S
N
S
D
S
A
A
P
G
L
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZA9
269
29172
G184
S
L
G
A
N
P
K
G
G
T
L
G
L
A
A
Rat
Rattus norvegicus
NP_001020235
178
19233
H94
S
L
G
T
D
P
K
H
G
A
L
G
L
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518492
261
26811
G175
P
L
G
G
S
G
E
G
G
A
P
P
L
D
A
Chicken
Gallus gallus
XP_417232
280
30888
A188
L
S
S
D
N
G
E
A
S
K
L
L
L
D
A
Frog
Xenopus laevis
Q4V7R0
275
30639
S184
E
P
T
I
F
G
E
S
R
D
V
T
L
D
A
Zebra Danio
Brachydanio rerio
Q29RA5
256
28162
D172
A
P
A
G
L
A
N
D
G
V
S
S
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784615
238
26671
G154
D
A
T
T
S
A
D
G
N
L
T
H
V
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.5
72.4
N.A.
72.2
43.7
N.A.
37.7
56
51.6
40.3
N.A.
N.A.
N.A.
N.A.
31.1
Protein Similarity:
100
99.2
98.1
77.8
N.A.
84.8
54.4
N.A.
51.4
72.8
68.3
58.1
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
100
86.6
53.3
N.A.
46.6
33.3
N.A.
26.6
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
66.6
N.A.
46.6
40
N.A.
40
40
33.3
40
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
10
10
0
19
0
10
10
28
0
0
0
37
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
10
0
46
10
0
10
0
0
0
28
0
% D
% Glu:
10
0
19
0
0
0
28
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
28
19
0
28
0
28
64
0
0
55
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
0
0
19
0
0
0
19
0
0
10
0
0
0
0
0
% K
% Leu:
10
28
0
0
10
0
0
0
0
10
28
10
82
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
55
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
10
28
0
0
0
19
0
0
0
0
46
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
46
37
10
10
19
37
0
46
10
0
10
10
0
0
0
% S
% Thr:
0
0
19
19
0
0
0
0
0
10
10
10
0
10
0
% T
% Val:
0
0
0
28
0
0
0
0
0
19
10
0
19
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _